Advanced techniques for detecting protein misfolding and aggregation in cellular environments
Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …
Application of biomarker-derived fluorescent probes for the detection of Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of beta-amyloid (Aβ) protein and neurofibrillary tangles in the brain, resulting …
accumulation of beta-amyloid (Aβ) protein and neurofibrillary tangles in the brain, resulting …
Small molecular fluorescent probes for Alzheimer's disease associated active species
F Tang, K Wang, X Liu, X Zhang, W Zhou… - … A European Journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the main
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …
A novel H2O2-activated NIR fluorescent probe for imaging β-amyloid fibrils and mitochondrial viscosity
Alzheimer's disease (AD) is an incurable chronic neurodegenerative disease. Until now, β-
amyloid, mitochondrial viscosity and the relatively high concentration of hydrogen peroxide …
amyloid, mitochondrial viscosity and the relatively high concentration of hydrogen peroxide …
[HTML][HTML] A FRET pair for quantitative and superresolution imaging of amyloid fibril formation
Á Ruiz-Arias, R Jurado, F Fueyo-González… - Sensors and Actuators B …, 2022 - Elsevier
The presence of neuritic plaques and amyloid fibrils arising from the misfolding of certain
proteins is the principal molecular indicator of neurodegenerative diseases such as …
proteins is the principal molecular indicator of neurodegenerative diseases such as …
A NIR iridium (III) complex-based reversible probe for assessing AD progression and screening anti-AD drugs through visualization of the “Cu2+-H2S seesaw” …
C Liu, M Qin, S Xu, Y Yuan, K Li, J Tang - Sensors and Actuators B …, 2024 - Elsevier
The progression of Alzheimer's disease (AD) is accompanied by the increase of copper ions
(Cu 2+) concentration and decrease of hydrogen sulfide (H 2 S) level in brain tissue, thus …
(Cu 2+) concentration and decrease of hydrogen sulfide (H 2 S) level in brain tissue, thus …
A Review on Recent Advances in Peptide‐based Fluorescence Probes and their Potential Applications
B Wang, L Wang, C Chen, Y Zhang, J Gao… - …, 2023 - Wiley Online Library
With the development and maturity of classical solid‐state synthesis techniques, peptide
synthesis has become more convenient. With the continuous progress of research in the …
synthesis has become more convenient. With the continuous progress of research in the …
Insights into Brain Tumor Diagnosis: Exploring In Situ Hybridization Techniques
E Namiot, GM Zembatov, PP Tregub - Frontiers in Neurology, 2024 - frontiersin.org
Our review examines genetic alterations in various brain tumors, drawing from both standard
literature searches and the Online Mendelian Inheritance in Man (OMIM) database (513 …
literature searches and the Online Mendelian Inheritance in Man (OMIM) database (513 …
Light‐controlled molecular tweezers capture specific amyloid oligomers
C Qian, J Chen, C Wang, Q Wang, X Wang… - Aggregate, 2024 - Wiley Online Library
Amyloid‐β peptide (Aβ) oligomers, characteristic symptom of Alzheimer's disease (AD), have
been identified as the most neurotoxic species and significant contributors to …
been identified as the most neurotoxic species and significant contributors to …
Light-Driven Capture of Specific Amyloid Oligomers
C Qian, J Chen, F Gao, T Xian, Q Wang, T Yang… - Available at SSRN … - papers.ssrn.com
Amyloid-β peptide (Aβ) oligomers are characteristic symptom of Alzheimer's disease (AD).
The development of powerful methods for arresting specific Aβ oligomers remains to be a …
The development of powerful methods for arresting specific Aβ oligomers remains to be a …