Polymer-based hydrogels are hydrophilic polymer networks with crosslinks widely applied
for drug delivery applications because of their ability to hold large amounts of water and …

Stimuli-responsive nanocarriers have the potential to revolutionize cancer treatment by
allowing precise delivery of drugs to the site of disease. The use of polymeric nanocarriers …

Adenosine triphosphate-binding cassette (ABC) transporters, such as multidrug resistance
protein 1 (MRP1), protect against cellular toxicity by exporting xenobiotic compounds across …

The prevalence of antimicrobial resistance (AMR) has been rising quickly in recent years.
AMR has emerged as a significant obstacle to the treatment of infectious diseases, and …

Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being
extensively studied due to their excellent delivery performance. Compared with other …

Given the widespread demand for novel antibacterial agents, we modified a cell-penetrating
peptide (KFF) 3K to transform it into an antibacterial peptide. Namely, we inserted a …

Uncontrolled accumulation of extracellular matrix leads to tissue fibrosis and loss of organ
function. We previously demonstrated in vitro that the DNA/RNA-binding protein fused in …

Antisense oligonucleotide-based (ASO) therapeutics have emerged as a promising strategy
for the treatment of human disorders. Charge-neutral PMOs have promising biological and …

Arsenic, in the simple form of arsenic trioxide, is currently marketed for the treatment of acute
promyelocytic leukemia. Due to the multifaceted mechanisms of action of arsenic, it has also …

Triple-negative breast cancer (TNBC) is an extremely aggressive subtype associated with a
poor prognosis. At present, the treatment for TNBC mainly relies on surgery and traditional …