Nucleic acids are excellent at recognizing complementary sequences through the formation
of Watson− Crick base pairs. Since the base pairing enables the highly selective …

Expressed genes are scanned by translocating RNA polymerases, which sensitively detect
DNA damage and initiate transcription-coupled repair (TCR), a subpathway of nucleotide …

A complete understanding of DNA double-helical structure discovered by James Watson
and Francis Crick in 1953, unveil the importance and significance of DNA. For the last seven …

Repetitive DNA motifs are abundant in the genomes of various species and have the
capacity to adopt non-canonical (ie, non-B) DNA structures. Several non-B DNA structures …

In contrast to B-DNA that has a right-handed double helical structure with Watson–Crick
base pairing under the ordinary physiological conditions, repetitive DNA sequences under …

DNA structure is a critical element in determining its function. The DNA molecule is capable
of adopting a variety of non-canonical structures, including three-stranded (ie triplex) …

Molecular evolution offers an insightful theory to interpret the genomic consequences of
thermal adaptation to previous events of climate change beyond range shifts. However …

The four natural DNA bases (A, T, G and C) associate in base pairs (A= T and G≡ C),
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …

DNA inverted repeats (IRs) are hotspots of genomic instability in both prokaryotes and
eukaryotes. This feature is commonly attributed to their ability to fold into hairpin-or cruciform …

Recent discoveries have revealed that simple repeating DNA sequences, which are known
to adopt non-B DNA conformations (such as triplexes, cruciforms, slipped structures, left …