Systemic complications of acromegaly and the impact of the current treatment landscape: an update

MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College …

Developed in Collaboration With the European … - Journal of the American …, 2006 - jacc.org
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and
the Prevention of Sudden Cardiac Death: A Report of the American College of …

Systemic complications of acromegaly: epidemiology, pathogenesis, and management

A Colao, D Ferone, P Marzullo, G Lombardi - Endocrine reviews, 2004 - academic.oup.com
This review focuses on the systemic complications of acromegaly. Mortality in this disease is
increased mostly because of cardiovascular and respiratory diseases, although currently …

The GH–IGF‐I axis and the cardiovascular system: clinical implications

A Colao - Clinical endocrinology, 2008 - Wiley Online Library
Summary Background GH and IGF‐I affect cardiac structure and performance. In the general
population, low IGF‐I has been associated with higher prevalence of ischaemic heart …

Pathogenesis and prevalence of hypertension in acromegaly

M Bondanelli, MR Ambrosio, EC degli Uberti - Pituitary, 2001 - Springer
Hypertension is an important complication of acromegaly, contributing to the increased
morbidity and mortality of this condition. Prevalence of hypertension in acromegalic patients …

Cardiovascular involvement in patients affected by acromegaly: an appraisal

S Mosca, S Paolillo, A Colao, E Bossone… - International journal of …, 2013 - Elsevier
Cardiovascular complications are frequent in acromegalic patients. Several studies reported
increased prevalence of traditional cardiovascular risk factors and early development of …

High prevalence of cardiac valve disease in acromegaly: an observational, analytical, case-control study

A Colao, L Spinelli, P Marzullo… - The Journal of …, 2003 - academic.oup.com
To characterize mitral and aortic valve abnormalities we performed M-mode, two-
dimensional, and pulsed Doppler echocardiography in 42 patients with active acromegaly …

The cardiovascular system in growth hormone excess and growth hormone deficiency

G Lombardi, C Di Somma, LFS Grasso… - Journal of …, 2012 - Springer
The clinical conditions associated with GH excess and GH deficiency (GHD) are known to
be associated with an increased risk for the cardiovascular morbidity and mortality …

The long‐term efficacy of conventional radiotherapy in patients with GH‐secreting pituitary adenomas

G Minniti, ML Jaffrain‐Rea, M Osti… - Clinical …, 2005 - Wiley Online Library
Objective To assess the long‐term efficacy and safety of conventional radiotherapy (RT) in
the control of acromegaly according to recent stringent criteria of cure. Design A …

Cardiovascular comorbidities in acromegaly: an update on their diagnosis and management

AM Ramos-Leví, M Marazuela - Endocrine, 2017 - Springer
Comorbidities related to the cardiovascular system are one of the most prevalent in patients
with acromegaly, and contribute to an increased risk of morbidity and all-cause mortality …