Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

As advances in prehospital and acute hospital care conquered the so-called golden hour,
multiple organ failure (MOF) emerged as the leading cause of late trauma death. 1–3 …

Abstract Background Coronavirus disease 2019 (COVID-19) is a respiratory disease
associated with endotheliitis and microthrombosis. Objectives To correlate endothelial …

Platelets are essential for physiological hemostasis and are central in pathological
thrombosis. These are their traditional and best known activities in health and disease. In …

A low platelet count is a frequently encountered haematological abnormality in patients
treated in intensive treatment units (ITU s). Although severe thrombocytopenia (platelet …

Objectives: Platelet activation plays an active role in the pathogenesis of acute respiratory
distress syndrome. In our prior study of 575 patients at high risk for acute respiratory distress …

Sepsis is a common condition that is associated with significant morbidity, mortality and
health-care cost. Pulmonary and non-pulmonary sepsis are common causes of the acute …

Introduction Acute respiratory distress syndrome (ARDS) is a common clinical syndrome
with high mortality and long-term morbidity. To date there is no effective pharmacological …

As aerobic organisms, we are continuously and throughout our lifetime subjected to an
oxidizing atmosphere and, most often, to environmental threats. The lung is the internal …

BACKGROUND Venous thromboembolic (VTE) disease has a high incidence following
trauma, but debate remains regarding optimal prophylaxis. Thrombelastography (TEG) has …