The growth of amyloid fibrils from Aβ1–42 peptide, one of the key pathogenic players in
Alzheimer's disease, is believed to follow a nucleation–elongation mechanism. Fibril …

Alzheimer's disease (AD), a slow progressive form of dementia, is clinically characterized by
cognitive dysfunction and memory impairment and neuropathologically characterized by the …

Amyloid-β peptide (Aβ) aggregation, one of the major hallmarks of Alzheimer's disease (AD),
has been commonly recognized as the critical culprit in AD etiology. However, the exact …

The accumulation of fibrillar amyloid-β (Aβ) aggregates in the brain, predominantly
comprising 40-and 42-residue amyloid-β (Aβ40 and Aβ42), is a major pathological hallmark …

Aβ (1-42) peptide is a neurotoxic agent strongly associated with the etiology of Alzheimer's
disease (AD). Current treatments are still of very low effectiveness, and deaths from AD are …

Neurodegenerative diseases are usually characterized by plaques made of well-ordered
aggregates of distinct amyloid proteins. Dissociating these very stable amyloid plaques is a …

Amyloid plaques are one of the principal hallmarks of Alzheimer's disease and are mainly
composed of Aβ amyloid peptides together with other components such as lipids, cations, or …

The dynamic process of formation of protein assemblies is essential to form highly ordered
structures in biological systems. Advances in structural and synthetic biology have led to the …

Amyloid and amorphous aggregates represent the two major categories of aggregates
associated with diseases, and although exhibiting distinct features, researchers often treat …

RNA aptamers have garnered attention for diagnostic applications due to their ability to
recognize diverse targets. Oligomers of 42-mer amyloid β-protein (Aβ42), whose …