Obesity is characterized by an energy imbalance and by the accumulation of visceral
adipose tissue. The energy balance is controlled by a complex set of balanced physiological …

Hypocretin (also called orexin) regulates various functions, such as sleep-wake rhythms,
attention, cognition, and energy balance, which show significant changes in schizophrenia …

Background/Purpose Orexin-A levels are reportedly increased in antipsychotic (APD)-
treated patients with schizophrenia compared to healthy controls and have been associated …

This study starts from the metabolic related indexes and cellular inflammatory factors in
patients with chronic schizophrenia to find out that it can be used as an effective screening …

The main findings of this review highlight that androgen administration increases
inflammatory mediators, altering different biochemical parameters. The results concerning …

The orexin system regulates a variety of physiological functions, including the sleep-wake
cycle, addiction, foraging behavior,, stress and cognitive functioning. Orexin levels in central …

Even though obese individuals often succeed with weight loss, long-term weight loss
maintenance remains elusive. Dietary, lifestyle and psychosocial correlates of weight loss …

Rationale Prepulse inhibition (PPI) impairment reflects sensorimotor gating problems, ie in
schizophrenia. This study aims to enlighten the role of orexinergic regulation on PPI in a …

Orexin-A and brain-derived neurotrophic factor (BDNF) are implicated in regulating
metabolic syndrome (MetS) and cognitive impairment of schizophrenia. However, the …

The term “pain threshold” refers to the measurement of the intensity of a physical stimulus
that evokes pain. To estimate the pain threshold, a mechanical or electrical stimulus with …