Bone metastasis of a predominantly osteoblastic (sclerotic) nature is the outcome for the vast
majority of patients with castration-resistant prostate cancer (CRPC). Pathologically …

Androgen ablative therapy is the cornerstone of treatment for metastatic prostate cancer and
some cases of high-risk, localized disease. This is only palliative, however, since castration …

RESUMO O envelhecimento e a obesidade favorecem o desenvolvimento de alterações em
diversos parâmetros sistêmicos bem como no aparelho reprodutor masculino. Em …

La conducta sexual de la rata macho influye en la fisiología de glándulas sexuales
accesorias tales como la próstata. Las hormonas esteroides participan tanto en la conducta …

Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation
therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term …

The monograph is devoted to the analysis of disorders of structural and functional
homeostasis of the testes and prostate that develop in experimental animals in response to …

Currently, prostate cancer is the number one cause of mortality in men in Mexico, and
number two globally (Meneses-Garcia et al. 2012; Li et al. 2016). Thus, there is an …

Abstract Multi-drug resistance (MDR)-ATP binding cassette (ABC) transporters, ABCB1,
ABCC1 and ABCG2 participate in the efflux of steroid hormones, estrogens and androgens …

Bone metastasis of a predominantly osteoblastic (sclerotic) nature is the outcome for the vast
majority of patients with castration-resistant prostate cancer (CRPC). Pathologically …

Sonic hedgehog (SHH) signaling regulates adult stem cells in many self-renewing organs
and its dysregulation has been linked to a variety of epithelial cancers. However, whether …