Vascular remodeling is a common pathological hallmark of many cardiovascular diseases.
Vascular smooth muscle cells (VSMCs) are the predominant cell type lining the tunica media …

The pathophysiology of vascular disease is linked to accelerated biological aging and a
combination of genetic, lifestyle, biological, and environmental risk factors. Within the …

Mitochondrial dynamics, including fission and fusion processes, are essential for heart
health. Mitochondria, the powerhouses of cells, maintain their integrity through continuous …

The heart is dependent on ATP production in mitochondria, which is closely associated with
cardiovascular disease because of the oxidative stress produced by mitochondria …

Irisin, a new exercise-mediated myokine, plays an important role in cardiovascular diseases
by regulating cell energy metabolism. The induction of mitochondrial dysfunction and …

Arterial remodeling is a common pathological basis of cardiovascular diseases such as
atherosclerosis, vascular restenosis, hypertension, pulmonary hypertension, aortic …

Disorders of cardiomyocyte metabolism play a crucial role in many cardiovascular diseases,
such as myocardial infarction, heart failure and ischemia–reperfusion injury. In myocardial …

Adipokines are biologically active factors secreted by adipose tissue that act on local and
distant tissues through autocrine, paracrine, and endocrine mechanisms. However …

Mitochondria are “cellular power stations” and essential organelles for maintaining cellular
homeostasis. Dysfunctional mitochondria have emerged as a key factor in the occurrence …

Objective NLRP3 inflammasome-mediated pyroptosis of macrophage acts essential roles in
the progression of sepsis-induced acute lung injury (ALI). Tangeretin (TAN), enriched in …