Evolutionarily older brain systems, such as the limbic system, appear to serve fundamental
aspects of emotional processing and provide relevant and motivational information for …

There is evidence for stressor-and brain region-specific selectivity in serotonergic
transmission responses to aversive stimuli. The aim of the present review is to provide an …

We developed a family of genetically encoded serotonin (5-HT) sensors (sDarken) on the
basis of the native 5-HT1A receptor and circularly permuted GFP. sDarken 5-HT sensors are …

Abstract The 5‐HT1A and 5‐HT1B receptors of serotonin play important roles as auto‐and
heteroreceptors controlling the release of serotonin itself and of other neurotransmitters …

5-Hydroxytryptamine (5-HT) is an important molecule in the brain that is implicated in mood
and emotional processes. In vivo, its dynamic release and uptake kinetics are poorly …

This review focuses on nicotinic–serotonergic interactions in the central nervous system
(CNS). Nicotine increases 5-hydroxytryptamine (5-HT) release in the cortex, striatum …

Repeated episodes of binge-like alcohol consumption produce anxiety, depression and
various deleterious effects including alterations in neurogenesis. While the involvement of …

Alzheimer's disease (AD) is the most common neurodegenerative disorder and there is
currently no cure. Neural circuit dysfunction is the fundamental mechanism underlying the …

Depression and anxiety disorders are among the leading causes of morbidity, mortality, and
disability in the United States. Impaired serotonin neurotransmission appears to be a central …

In vivo microdialysis is widely used to investigate how neurotransmitter levels in the brain
respond to biologically relevant challenges. Here, we combined recent improvements in the …