Since the work of Judah Folkman in the 1970s demonstrating the importance of
vascularization on tumour growth the many roles played by tumour stroma have been …

It has become evident that a closely regulated presence of vascular endothelial growth
factor (VEGF) and angiopoietin (Ang) factors determines the fate of blood vessel formation …

Intracellular localization has been reported for over three‐quarters of receptor tyrosine
kinase (RTK) families in response to environmental stimuli. Internalized RTK may bind to …

purpose. To elucidate the potential role of angiopoietins and the Tie2 system in choroidal
neovascularization. methods. Surgically excised choroidal neovascular membranes …

Capillary hemangioblastomas and hemangiopericytomas are highly vascular central
nervous system tumors of controversial origin. Of interest in their pathogenesis are …

The expansion or remodelling of pre-existing blood vessels, known as angiogenesis, by
either nascent sprouting, intercalated or intussusceptive growth is a highly regulated …

The ability of small blood vessels to undergo rapid, reversible morphological changes is
essential for the adaptive response to tissue injury or local infection. A canonical feature of …

Protein ligands and receptor tyrosine kinases that specifically regulate endothelial cell
function are mainly involved in physiological as well as in disease-related angiogenesis …

Background Vascular endothelial growth factor (VEGF) is an important regulator of
endothelial cell proliferation, migration, and permeability during embryonic vasculogenesis …

Endothelial receptor tyrosine kinases may play important roles in pathological vascular
growth, particularly in tumours. In this study, immunohistochemistry was used to evaluate the …