Metformin: historical overview
CJ Bailey - Diabetologia, 2017 - Springer
Metformin (dimethylbiguanide) has become the preferred first-line oral blood glucose-
lowering agent to manage type 2 diabetes. Its history is linked to Galega officinalis (also …
lowering agent to manage type 2 diabetes. Its history is linked to Galega officinalis (also …
Metformin: clinical use in type 2 diabetes
E Sanchez-Rangel, SE Inzucchi - Diabetologia, 2017 - Springer
Metformin is one of the most popular oral glucose-lowering medications, widely considered
to be the optimal initial therapy for patients with type 2 diabetes mellitus. Interestingly, there …
to be the optimal initial therapy for patients with type 2 diabetes mellitus. Interestingly, there …
Treatment of diabetes in older adults: an Endocrine Society clinical practice guideline
D LeRoith, GJ Biessels, SS Braithwaite… - The Journal of …, 2019 - academic.oup.com
Objective The objective is to formulate clinical practice guidelines for the treatment of
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …
Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update …
A Qaseem, TJ Wilt, D Kansagara… - Annals of internal …, 2018 - acpjournals.org
Description: The American College of Physicians developed this guidance statement to
guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes. Methods …
guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes. Methods …
Potential impact of the multi-target drug approach in the treatment of some complex diseases
It is essential to acknowledge the efforts made thus far to manage or eliminate various
disease burden faced by humankind. However, the rising global trends of the so-called …
disease burden faced by humankind. However, the rising global trends of the so-called …
[HTML][HTML] 2022 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the management of hypertension
Hypertension is the most important modifiable cause of cardiovascular (CV) disease and all-
cause mortality worldwide. Despite the positive correlations between blood pressure (BP) …
cause mortality worldwide. Despite the positive correlations between blood pressure (BP) …
Type 2 diabetes in the real world: the elusive nature of glycemic control
SV Edelman, WH Polonsky - Diabetes care, 2017 - Am Diabetes Assoc
Despite US Food and Drug Administration (FDA) approval of over 40 new treatment options
for type 2 diabetes since 2005, the latest data from the National Health and Nutrition …
for type 2 diabetes since 2005, the latest data from the National Health and Nutrition …
Preparation of bioactive peptides with antidiabetic, antihypertensive, and antioxidant activities and identification of α‐glucosidase inhibitory peptides from soy protein
R Wang, H Zhao, X Pan, C Orfila, W Lu… - Food science & …, 2019 - Wiley Online Library
In this study, the peptides of soy protein obtained by enzymatic digestion with proteases
were analyzed for their antidiabetic, antihypertensive, and antioxidant activities. Peptides …
were analyzed for their antidiabetic, antihypertensive, and antioxidant activities. Peptides …
Newer pharmacologic treatments in adults with type 2 diabetes: a systematic review and network meta-analysis for the American College of Physicians
T Drake, A Landsteiner, L Langsetmo… - Annals of internal …, 2024 - acpjournals.org
Background: Newer diabetes medications may have beneficial effects on mortality,
cardiovascular outcomes, and renal outcomes. Purpose: To evaluate the effectiveness …
cardiovascular outcomes, and renal outcomes. Purpose: To evaluate the effectiveness …
An updated review on food‐derived bioactive peptides: Focus on the regulatory requirements, safety, and bioavailability
Food‐derived bioactive peptides (BAPs) are recently utilized as functional food raw
materials owing to their potential health benefits. Although there is a huge amount of …
materials owing to their potential health benefits. Although there is a huge amount of …