[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges

AD Singhi, EJ Koay, ST Chari, A Maitra - Gastroenterology, 2019 - Elsevier
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …

ACG clinical guideline: diagnosis and management of pancreatic cysts

GH Elta, BK Enestvedt, BG Sauer… - Official journal of the …, 2018 - journals.lww.com
Pancreatic cysts are very common with the majority incidentally identified. There are several
types of pancreatic cysts; some types can contain cancer or have malignant potential …

Burden of pancreatic cancer: from epidemiology to practice

N Khalaf, HB El-Serag, HR Abrams, AP Thrift - Clinical Gastroenterology …, 2021 - Elsevier
Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide with
432,242 related deaths in 2018. Unlike other cancers, the incidence of pancreatic cancer …

Cancer overdiagnosis: a biological challenge and clinical dilemma

S Srivastava, EJ Koay, AD Borowsky… - Nature Reviews …, 2019 - nature.com
For cancer screening to be successful, it should primarily detect cancers with lethal potential
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …

American gastroenterological association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts

SS Vege, B Ziring, R Jain, P Moayyedi… - …, 2015 - gastrojournal.org
This article has an accompanying continuing medical education activity on page e12.
Learning Objective: At the conclusion of this exercise, the learner will understand the …

Early detection of pancreatic cancer using DNA-based molecular approaches

AD Singhi, LD Wood - Nature Reviews Gastroenterology & Hepatology, 2021 - nature.com
Due to its poor prognosis and the late stage at which it is typically diagnosed, early detection
of pancreatic cancer is a pressing clinical problem. Advances in genomic analysis of human …

Long-term risk of malignancy in branch-duct intraductal papillary mucinous neoplasms

H Oyama, M Tada, K Takagi, K Tateishi, T Hamada… - Gastroenterology, 2020 - Elsevier
Background & Aims Long-term outcomes of patients with branch-duct intraductal papillary
mucinous neoplasms (IPMNs), particularly those after 5 years of surveillance, have not been …

AGA clinical practice update on pancreas cancer screening in high-risk individuals: expert review

HR Aslanian, JH Lee, MI Canto - Gastroenterology, 2020 - Elsevier
Description The purpose of this American Gastroenterological Association Institute Clinical
Practice Update is to describe the indications for screening for pancreas cancer in high-risk …

[HTML][HTML] Prospective, multi-institutional, real-time next-generation sequencing of pancreatic cyst fluid reveals diverse genomic alterations that improve the clinical …

A Paniccia, PM Polanco, BA Boone, AI Wald… - Gastroenterology, 2023 - Elsevier
Background & Aims Next-generation sequencing (NGS) of pancreatic cyst fluid is a useful
adjunct in the assessment of patients with pancreatic cyst. However, previous studies have …

Management of incidental pancreatic cysts: a white paper of the ACR Incidental Findings Committee

AJ Megibow, ME Baker, DE Morgan, IR Kamel… - Journal of the American …, 2017 - Elsevier
Abstract The ACR Incidental Findings Committee (IFC) presents recommendations for
managing pancreatic cysts that are incidentally detected on CT or MRI. These …