We report on the rapid and specific detection of bacteria commonly isolated from clinical
specimens from cystic fibrosis (CF) patients by fluorescent in situ hybridization (FISH). On …

In many genetic disorders, the responsible gene and its protein product are unknown. The
technique known as" reverse genetics," in which chromosomal map positions and …

Only about 30% of the cystic fibrosis chromosomes in the Israeli cystic fibrosis patient
populations carry the major CF mutation (ΔF508). Since different Jewish ethnic groups …

It has been clear since the rediscovery of Mendel that humans obey laws of heredity
identical with those of other organisms. The central features of Mendelism were observable …

Background Cystic fibrosis is a life-limiting autosomal recessive disorder with a highly
variable clinical presentation. The classic form involves characteristic findings in the …

Abstract In June 1998, a Steering and Revisions Committee of the International Institute for
the Unification of Private Law (Unidroit) fleshed out the final version of a" Draft Unidroit …

The paraoxonase gene family contains at least three members, including PON1, PON2 and
PON3, which are located on chromosome 7q21. 3-22.1. Until recently, there has been little …

Recent developments in molecular and statistical methods have made it possible to identify
the genetic basis of any biological trait and have given rise to spectacular advances in the …

The positional cloning of the gene responsible for cystic fibrosis (CF) was the important first
step in understanding the basic defect and pathophysiology of the disease. This study aims …

Prognosis of patients with cystic fibrosis (CF) varies extensively despite recent advances in
targeted therapies that improve CF transmembrane conductance regulator (CFTR) function …