Doxorubicin—an agent with multiple mechanisms of anticancer activity

M Kciuk, A Gielecińska, S Mujwar, D Kołat… - Cells, 2023 - mdpi.com
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …

[HTML][HTML] Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization

G Sanità, B Carrese, A Lamberti - Frontiers in molecular biosciences, 2020 - frontiersin.org
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …

[HTML][HTML] Ultrasmall gold nanoparticles in cancer diagnosis and therapy

M Fan, Y Han, S Gao, H Yan, L Cao, Z Li, XJ Liang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Due to their lower systemic toxicity, faster kidney clearance and higher tumor accumulation,
ultrasmall gold nanoparticles (less than 10 nm in diameter) have been proved to be …

Synergic effects of nanoparticles-mediated hyperthermia in radiotherapy/chemotherapy of cancer

K Mortezaee, A Narmani, M Salehi, H Bagheri… - Life sciences, 2021 - Elsevier
The conventional cancer treatment modalities such as radiotherapy and chemotherapy
suffer from several limitations; hence, their efficiency needs to be improved with other …

Antibody‐incorporated nanomedicines for cancer therapy

SY Wu, FG Wu, X Chen - Advanced Materials, 2022 - Wiley Online Library
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …

Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times

C Bailly, X Thuru, B Quesnel - NAR cancer, 2020 - academic.oup.com
Monoclonal antibodies targeting programmed cell death 1/programmed cell death ligand 1
(PD-1/PD-L1) immune checkpoints have improved the treatments of cancers. However, not …

ROS-based dynamic therapy synergy with modulating tumor cell-microenvironment mediated by inorganic nanomedicine

X Zhong, X Wang, J Li, J Hu, L Cheng… - Coordination Chemistry …, 2021 - Elsevier
Dynamic therapy (DT) by in situ ROS generation is emerging as an attractive therapeutic
modality with potential to treat deep-seated tumors, avoiding side effects to healthy tissues …

Next-generation engineered nanogold for multimodal cancer therapy and imaging: a clinical perspectives

M Alle, G Sharma, SH Lee, JC Kim - Journal of nanobiotechnology, 2022 - Springer
Cancer is one of the significant threats to human life. Although various latest technologies
are currently available to treat cancer, it still accounts for millions of death each year …

Combination of phototherapy with immune checkpoint blockade: Theory and practice in cancer

Y Zhao, X Liu, X Liu, J Yu, X Bai, X Wu, X Guo… - Frontiers in …, 2022 - frontiersin.org
Immune checkpoint blockade (ICB) therapy has evolved as a revolutionized therapeutic
modality to eradicate tumor cells by releasing the brake of the antitumor immune response …

Delivery of cancer therapies by synthetic and bio-inspired nanovectors

T Briolay, T Petithomme, M Fouet, N Nguyen-Pham… - Molecular Cancer, 2021 - Springer
Background As a complement to the clinical development of new anticancer molecules,
innovations in therapeutic vectorization aim at solving issues related to tumor specificity and …