Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
[HTML][HTML] Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …
[HTML][HTML] Ultrasmall gold nanoparticles in cancer diagnosis and therapy
Due to their lower systemic toxicity, faster kidney clearance and higher tumor accumulation,
ultrasmall gold nanoparticles (less than 10 nm in diameter) have been proved to be …
ultrasmall gold nanoparticles (less than 10 nm in diameter) have been proved to be …
Synergic effects of nanoparticles-mediated hyperthermia in radiotherapy/chemotherapy of cancer
The conventional cancer treatment modalities such as radiotherapy and chemotherapy
suffer from several limitations; hence, their efficiency needs to be improved with other …
suffer from several limitations; hence, their efficiency needs to be improved with other …
Antibody‐incorporated nanomedicines for cancer therapy
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …
achieved considerable success and progress over the past decades. Nevertheless …
Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times
Monoclonal antibodies targeting programmed cell death 1/programmed cell death ligand 1
(PD-1/PD-L1) immune checkpoints have improved the treatments of cancers. However, not …
(PD-1/PD-L1) immune checkpoints have improved the treatments of cancers. However, not …
ROS-based dynamic therapy synergy with modulating tumor cell-microenvironment mediated by inorganic nanomedicine
Dynamic therapy (DT) by in situ ROS generation is emerging as an attractive therapeutic
modality with potential to treat deep-seated tumors, avoiding side effects to healthy tissues …
modality with potential to treat deep-seated tumors, avoiding side effects to healthy tissues …
Next-generation engineered nanogold for multimodal cancer therapy and imaging: a clinical perspectives
M Alle, G Sharma, SH Lee, JC Kim - Journal of nanobiotechnology, 2022 - Springer
Cancer is one of the significant threats to human life. Although various latest technologies
are currently available to treat cancer, it still accounts for millions of death each year …
are currently available to treat cancer, it still accounts for millions of death each year …
Combination of phototherapy with immune checkpoint blockade: Theory and practice in cancer
Y Zhao, X Liu, X Liu, J Yu, X Bai, X Wu, X Guo… - Frontiers in …, 2022 - frontiersin.org
Immune checkpoint blockade (ICB) therapy has evolved as a revolutionized therapeutic
modality to eradicate tumor cells by releasing the brake of the antitumor immune response …
modality to eradicate tumor cells by releasing the brake of the antitumor immune response …
Delivery of cancer therapies by synthetic and bio-inspired nanovectors
T Briolay, T Petithomme, M Fouet, N Nguyen-Pham… - Molecular Cancer, 2021 - Springer
Background As a complement to the clinical development of new anticancer molecules,
innovations in therapeutic vectorization aim at solving issues related to tumor specificity and …
innovations in therapeutic vectorization aim at solving issues related to tumor specificity and …