Role of viral infections in the development and exacerbation of asthma in children

T Jartti, JE Gern - Journal of allergy and clinical immunology, 2017 - Elsevier
Viral infections are closely linked to wheezing illnesses in children of all ages. Respiratory
syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is …

[HTML][HTML] More than just a barrier: the immune functions of the airway epithelium in asthma pathogenesis

A Frey, LP Lunding, JC Ehlers, M Weckmann… - Frontiers in …, 2020 - frontiersin.org
Allergic bronchial asthma is a chronic disease of the airways that is characterized by
symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute …

The role of respiratory syncytial virus‐and rhinovirus‐induced bronchiolitis in recurrent wheeze and asthma—a systematic review and meta‐analysis

H Makrinioti, K Hasegawa… - Pediatric Allergy and …, 2022 - Wiley Online Library
Introduction Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis.
RSV‐induced bronchiolitis has been associated with preschool wheeze and asthma in …

Respiratory syncytial virus—a comprehensive review

AT Borchers, C Chang, ME Gershwin… - Clinical reviews in allergy …, 2013 - Springer
Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

The airway epithelium: soldier in the fight against respiratory viruses

M Vareille, E Kieninger, MR Edwards… - Clinical microbiology …, 2011 - Am Soc Microbiol
The airway epithelium acts as a frontline defense against respiratory viruses, not only as a
physical barrier and through the mucociliary apparatus but also through its immunological …

Role of viral respiratory infections in asthma and asthma exacerbations

WW Busse, RF Lemanske, JE Gern - The Lancet, 2010 - thelancet.com
Viral respiratory tract infections are common and usually selflimited illnesses. For patients at
risk of asthma, or with existing asthma, viral respiratory tract infections can have a profound …

[HTML][HTML] Viral infections in allergy and immunology: how allergic inflammation influences viral infections and illness

MR Edwards, K Strong, A Cameron, RP Walton… - Journal of Allergy and …, 2017 - Elsevier
Viral respiratory tract infections are associated with asthma inception in early life and asthma
exacerbations in older children and adults. Although how viruses influence asthma inception …

Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life

N Sigurs, F Aljassim, B Kjellman, PD Robinson… - Thorax, 2010 - thorax.bmj.com
Background An increased prevalence of asthma/recurrent wheeze (RW), clinical allergy and
allergic sensitisation up to age 13 years has previously been reported in subjects …

Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children

DJ Jackson, RE Gangnon, MD Evans… - American journal of …, 2008 - atsjournals.org
Rationale: Virus-induced wheezing episodes in infancy often precede the development of
asthma. Whether infections with specific viral pathogens confer differential future asthma risk …

Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence

FJ Rubner, DJ Jackson, MD Evans… - Journal of Allergy and …, 2017 - Elsevier
Background Early life rhinovirus (RV) wheezing illnesses and aeroallergen sensitization
increase the risk of asthma at school age. Whether these remain risk factors for the …