Sodium-glucose co-transporter 2 (SGLT2) inhibitors

S Mifsud, EL Schembri, A Montebello… - Malta Medical …, 2020 - mmsjournals.org
Type 2 diabetes mellitus is a progressive metabolic disorder. Marked hyperglycaemia leads
to serious vascular complications. Hence, addressing this modifiable risk factor is of …

[PDF][PDF] Effect of dapagliflozin treatment on the expression of renal Na+ transporters/channels on high fat diet diabetic mice

C Ma, JHF de Baaij, PJ Millar, VA Gault… - Shedding light on …, 2020 - repository.ubn.ru.nl
Inhibition of the sodium/glucose co-transporter 2 (SGLT2) is a new therapeutic strategy for
diabetes. It is unclear how proximal loss of sodium (Na+)(and glucose) affects the …

[HTML][HTML] The Benefits of SGLT2 Inhibitors in Cardiovascular Prevention, Glycemic Control and Weight Loss, in the Treatment of Diabetes

B de Souza Faustino, ARC Junior… - Open Journal of …, 2016 - scirp.org
The sodium and glucose co-transporter inhibitors type 2 (SGLT2) comprises a new class of
hypoglycemic drugs to control type 2 diabetes mellitus, in an attempt to add new non …

Glyoxalase-1 gene transfer to prevent cerebral microvascular and neuronal dysfunctions in type 1 diabetes mellitus

FAM Alomar - 2014 - search.proquest.com
Individuals with diabetes mellitus (DM) are living longer thanks to an armamentarium of
glucose-lowering agents, nutrition and exercise strategies, and education initiatives …

Inibidores SGLT2: benefícios para além do controlo glicémico

DT Capitão - 2020 - search.proquest.com
Nesta dissertação pretende-se identificar e clarificar os principais benefícios dos inibidores
SGTL2 para além do controlo glicémico nomeadamente na diminuição do peso corporal, da …

[PDF][PDF] Clinical Features of Periodontal Abscess as Potential Additional Screening Criteria for Diabetes Mellitus in Malaysia.

SK Yeong, R Bin Yahaya, HK Chan - Malaysian Dental Journal, 2020 - researchgate.net
Background Although periodontal abscess is recommended to be used to guide the
screening for diabetes mellitus (DM), the information on their interactions is still limited. This …

Nephrological effects of SGLT2. What do we know so far?

E Salinas-Lezama, D Seniscal-Arredondo… - Medicina Interna de …, 2019 - medigraphic.com
Prevalence of type 2 diabetes has increased significantly. It is inferred that the number of
adults with diabetic nephropathy will also increase. Therefore, diabetic nephropathy will …

Effects of canagliflozin on renal and urinary angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) in db/db diabetic mice

UH Thanekar - 2019 - rave.ohiolink.edu
Diabetes is one of the major causes of chronic kidney disease (CKD) which could lead to
end-stage renal disease. Angiotensin-II (Ang-II), a major bioactive peptide of renin …

Renal Protective Effects of Empagliflozin via Inhibition of the EMT Program Associated with Suppression of Aberrant Glycolysis in Proximal Tubules

J Li, S Takagi, K Nitta, M Kitada… - Available at SSRN …, 2019 - papers.ssrn.com
Background: The sodium glucose co-transporter 2 (SGLT2) inhibitors are beneficial in
halting diabetic kidney disease, however complete mechanisms are not elucidated yet …

Efeitos pleiotrópicos do inibidor SGLT2, empagliflozina, em modelo experimental de esteatose hepática

TIP Silva - 2019 - bdtd.uerj.br
(Mestrado em Biologia Humana e Experimental)–Instituto de Biologia Roberto Alcântara
Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2019. A doença …