[HTML][HTML] Recent advances in understanding glucocorticoid receptor function in cancer
SD Conzen - Clinical advances in hematology & oncology: H&O, 2017 - ncbi.nlm.nih.gov
SC There are several new insights into the role of glucocorticoids, particularly regarding how
the glucocorticoid receptor functions in both normal and cancer cells. The glucocorticoid …
the glucocorticoid receptor functions in both normal and cancer cells. The glucocorticoid …
Molecular recognition of DNA by py–im polyamides: From discovery to oncology
PB Dervan, AA Kurmis, PB Finn - 2018 - books.rsc.org
The development of Py–Im polyamides as potential therapeutic agents is an example of the
application of fundamental science at all levels from initial concept, based on purely …
application of fundamental science at all levels from initial concept, based on purely …
Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633)
X Du, J Eksterowicz, H Zhou, Y Rew… - Journal of Medicinal …, 2019 - ACS Publications
Structure-based modification of mifepristone (1) led to the discovery of novel mifepristone
derivatives with improved selectivity profile. Addition of a methyl group at the C10 position of …
derivatives with improved selectivity profile. Addition of a methyl group at the C10 position of …
Sequence-selective Interactions of Actinomycin D with DNA: Discovery of a Thermodynamic Switch
JS Hudson, A Lucius, MJ Waring, DE Graves - 2018 - books.rsc.org
The interactions of actinomycin D with nucleic acids have served as a paradigm for DNA
base sequence selectivity for the past half century through its demonstrated preference for …
base sequence selectivity for the past half century through its demonstrated preference for …
The role of steroid hormone receptors in prostate cancer. A study of estrogen-and progesterone receptors in adenocarcinoma of the prostate
TKW Grindstad - 2018 - munin.uit.no
Steroid hormones and their receptors are vital for numerous physiological processes in the
human body, but also related to the development of several malignancies. One such …
human body, but also related to the development of several malignancies. One such …