Importance Early treatment initiation in multiple sclerosis (MS) is crucial in preventing
irreversible neurological damage and disability progression. The current assessment of …

Grey matter pathology is central to the progression of multiple sclerosis (MS). We discovered
that MS plasma immunoglobulin G (IgG) antibodies, mainly IgG1, form large aggregates (> …

Multiple sclerosis (MS) is an immune-mediated disease that targets the myelin sheath of
central nervous system (CNS) neurons leading to axon injury, neuronal death, and …

Intrathecal immunoglobulin G (IgG) and oligoclonal bands (OCBs) detected in both the brain
and cerebrospinal fluid (CSF) are seminal features of multiple sclerosis (MS). The presence …

Background: Immunoglobulin gamma (IgG) oligoclonal bands (OCB) in the cerebrospinal
fluid (CSF) are absent in a small group of multiple sclerosis (MS) patients. According to …

Introduction Myelin-oligodendrocyte glycoprotein antibody (MOG)–associated disorder
(MOGAD) is a recently identified immune-mediated inflammatory disorder of the central …

Multiple sclerosis (MS) is a chronic, autoimmune, demyelinating disease of the central
nervous system (CNS) that leads to axonal damage and accumulation of disability …

Background Intrathecal clonal expansion of antibody-producing plasma cells in multiple
sclerosis (MS) perpetuates central nervous system injury and is associated with active …

Increased intrathecal IgG and oligoclonal bands (OCB) are seminal features of multiple
sclerosis (MS). Although no such differences in MS blood total IgG antibodies have been …

Background A case-control study was conducted to analyze the role of cerebrospinal fluid
immunoglobulin in the differential diagnosis of autoimmune encephalitis and viral …