Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …

For more than 20 years, moderately raised concentrations of total homocysteine (tHcy) have
been associated with an increased risk of atherothrombotic vascular events but only recently …

This review will primarily address methodological aspects of homocysteine measurement,
highlighting changes since the subject was comprehensively reviewed in 1993, and will …

Homocysteine results from the transmethylation of methionine. Its metabolism depends
primarily on three enzymes and several vitamin cofactors. Genetic abnormality in these …

During the past year epidemiological studies have linked elevated plasma total
homocysteine concentrations with an increased risk of ischaemic stroke because of arterial …

OBJECTIVE: To report a case of vitamin B12 deficiency associated with long-term use (∼
4½ y) of histamine2 (H2)-receptor antagonists and a proton-pump inhibitor (PPI) in a patient …

Alcoholic liver disease is a major health care problem worldwide. Findings have
demonstrated that ethanol feeding impairs several of the multiple steps in methionine …

Previous studies showed that chronic ethanol administration inhibits methionine synthase
activity, resulting in impaired homocysteine remethylation to form methionine. This defect in …

Summary Background and Aim An adverse coronary risk profile has been reported amongst
rural-to-urban migrant population living in urban slums undergoing stressful socio-economic …

During the last 10-12 years, the research on homocysteine has become very active. About
1500 of articles are now published each year on homocysteine and the vitamins involved in …