Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

Cuproptosis is a new cell death that depends on copper (Cu) ionophores to transport Cu into
cancer cells, which induces cell death. However, existing Cu ionophores are small …

Hypoxia is a common feature of most solid tumors, which promotes the proliferation,
invasion, metastasis, and therapeutic resistance of tumors. Researchers have been …

Anti‐PD‐L1 monoclonal antibody has achieved substantial success in tumor
immunotherapy by T‐cells activation. However, the excessive accumulation of extracellular …

Background Bladder cancer is one of the most common malignant tumors of the urinary
system and is associated with a poor prognosis once invasion and distant metastases occur …

Background Bladder cancer (BC) is a disease with significant heterogeneity and poor
prognosis. The prognosis and therapeutic response of BC patients are significantly …

Most of the anticancer compounds synthesized by chemists are primarily evaluated for their
direct cytotoxic effects at the cellular level, often overlooking the critical role of the immune …

Abstract Adhesion-regulating molecule 1 (ADRM1) has been implicated in tumor
development, yet its specific role in bladder cancer (BC) remains undefined. This study …

Background Anti–programmed cell death 1 (anti–PD-1) and PD ligand 1 (PD-L1) immune
checkpoint therapies (ICTs) provided durable responses only in a subset of cancer patients …

Simple Summary Accurate prognostic assessment of bladder cancer patients is essential for
risk stratification, individualized therapeutic decision-making and follow-up management. In …