Cellular and molecular mechanisms of aflatoxin B1-mediated neurotoxicity: the therapeutic role of natural bioactive compounds

IA Adedara, OE Atanda, CSA Monteiro… - Environmental …, 2023 - Elsevier
Abstract Aflatoxin B 1 (AFB 1), a dietary toxin from the mold Aspergillus species, is well
acknowledged to elicit extra-hepatic toxicity in both animals and humans. The neurotoxicity …

[HTML][HTML] May phytophenolics alleviate aflatoxins-induced health challenges? A holistic insight on current landscape and future prospects

H Rasouli, FD Nayeri, R Khodarahmi - Frontiers in nutrition, 2022 - frontiersin.org
The future GCC-connected environmental risk factors expedited the progression of nCDs.
Indeed, the emergence of AFs is becoming a global food security concern. AFs are lethal …

[HTML][HTML] Artichoke (Cynara Scolymus) methanolic leaf extract alleviates diethylnitrosamine-induced toxicity in BALB/c mouse brain: involvement of oxidative stress and …

B Cicek, S Genc, Y Yeni, M Kuzucu, A Cetin… - Journal of Personalized …, 2022 - mdpi.com
(1) Background: Various epidemiological studies suggest that oxidative stress and disrupted
neuronal function are mechanistically linked to neurodegenerative diseases (NDs) …

[HTML][HTML] In vitro and in vivo assessment of AFB1 and OTA toxic effects and the beneficial role of bioactive compounds. A systematic review

M Frangiamone, Á Lázaro, A Cimbalo, G Font… - Food Chemistry, 2024 - Elsevier
The purpose of this review was to investigate the current knowledge about aflatoxin B1
(AFB1) and ochratoxin A (OTA) toxicity and the possible beneficial role of bioactive …

[HTML][HTML] Functional and Therapeutic Potential of Cynara scolymus in Health Benefits

C Porro, T Benameur, A Cianciulli, M Vacca, M Chiarini… - Nutrients, 2024 - mdpi.com
Dietary supplements enriched with bioactive compounds represent a promising approach to
influence physiological processes and enhance longevity and overall health. Cynara …

Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats

MA Nasef, MI Yousef, DA Ghareeb… - Drug and Chemical …, 2023 - Taylor & Francis
This study was conducted to investigate the protective potential of a pharmaceutically
formulated capsule of artichoke leaf powder (ArLP) against aflatoxin B1 (AFB1)-induced …

Artichoke (Cynara scolymus) leaf extract abates the neurotoxic and neurobehavioral outcomes of fluoride in Nile tilapia (Oreochromis niloticus) via balancing oxidative …

A Elsayyad, YA Reyad, BA Elshafey, EK Aziz… - Aquaculture, 2024 - Elsevier
This study assessed the effects of fluoride (FLO) on neurobehavioral function, brain
oxidative status and inflammatory response, acetylcholinesterase activity, and …

Neurotoxic Mechanisms of Mycotoxins: Focus on Aflatoxin B1 and T-2 Toxin

C Song, Z Wang, J Cao, Y Dong, Y Chen - Environmental Pollution, 2024 - Elsevier
Abstract Aflatoxin B1 (AFB1) and T-2 toxin are commonly found in animal feed and stored
grain, posing a serious threat to human and animal health. Mycotoxins can penetrate brain …

[HTML][HTML] An Overview of the Versatility of the Parts of the Globe Artichoke (Cynara scolymus L.), Its By-Products and Dietary Supplements

B Olas - Nutrients, 2024 - mdpi.com
Cynara scolymus, also known as the globe artichoke or artichoke, is grown as a food, mainly
in the Mediterranean, Canary Islands, and Egypt, as well as in Asia and South America. It …

[HTML][HTML] Bioactive Compounds, Health Benefits and Food Applications of Artichoke (Cynara scolymus L.) and Artichoke By-Products: A Review

P Ayuso, J Quizhpe, MÁ Rosell, R Peñalver, G Nieto - Applied Sciences, 2024 - mdpi.com
Cynara scolymus L. is an herbaceous plant originally from the western Mediterranean area,
with Italy, Spain and France the main being producers. Both the edible flowering head and …