Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation‐mediated apoptosis in human uterine cancer cells
M Yu, H Kong, Y Zhao, X Sun, Z Zheng… - Molecular …, 2014 - Wiley Online Library
Activation of telomerase is a key element in oncogenesis and resistance to apoptosis for
many cancers. Some histone deacetylase inhibitors (HDACi) or chemotheraputic agents …
many cancers. Some histone deacetylase inhibitors (HDACi) or chemotheraputic agents …
Suberoylanilide hydroxamic acid induces hypersensitivity to radiation therapy in acute myelogenous leukemia cells expressing constitutively active FLT3 mutants
X Chen, EH Radany, P Wong, S Ma, K Wu, B Wang… - PloS one, 2013 - journals.plos.org
Histone deacetylase inhibitors (HDIs) have shown promise as candidate radiosensitizer for
many types of cancers. However, the mechanisms of action are not well understood, and …
many types of cancers. However, the mechanisms of action are not well understood, and …
Histone deacetylase inhibitory activity of hydroxycapsaicin, a synthetic derivative of capsaicin, and its cytotoxic effects against human colon cancer cell lines
T Senawong, P Wongphakham… - Turkish Journal of …, 2015 - journals.tubitak.gov.tr
Capsaicin possesses cytotoxic/anticancer activity and shares some common structural
features, including a benzene ring and a long hydrophobic carbon tail, with the histone …
features, including a benzene ring and a long hydrophobic carbon tail, with the histone …
[PDF][PDF] Targeting the Difficult-to-Drug CD71 and MYCN with Gambogic Acid and Vorinostat in a Class of Neuroblastomas
KBKHA Sadra, SO Huh - Cell Physiol Biochem, 2019 - pdfs.semanticscholar.org
Abstract Background/Aims: Although neuroblastoma is a heterogeneous cancer, a
substantial portion overexpresses CD71 (transferrin receptor 1) and MYCN. This study …
substantial portion overexpresses CD71 (transferrin receptor 1) and MYCN. This study …
[HTML][HTML] Effects of histone deacetylase inhibitor panobinostat (LBH589) on bone marrow mononuclear cells of relapsed or refractory multiple myeloma patients and its …
Y Ma, W Liu, L Zhang, G Jia - Medical Science Monitor …, 2017 - ncbi.nlm.nih.gov
Effects of Histone Deacetylase Inhibitor Panobinostat (LBH589) on Bone Marrow Mononuclear
Cells of Relapsed or Refractory Multiple Myeloma Patients and Its Mechanisms - PMC Back to …
Cells of Relapsed or Refractory Multiple Myeloma Patients and Its Mechanisms - PMC Back to …
Suberoylanilide hydroxamic acid (SAHA) attenuates memory impairment in the offspring of rats exposed to sevoflurane anesthesia
X Song, XW Liu, J Wang - Biochemical and Biophysical Research …, 2023 - Elsevier
Background SAHA was reported to enhance the expression of miR-129-5p, which was
predicted to bind to 3'UTR of CASP-6, a gene playing crucial roles in the pathogenesis of …
predicted to bind to 3'UTR of CASP-6, a gene playing crucial roles in the pathogenesis of …
Structure-activity relationship studies of novel oxygen-incorporated SAHA analogues
SA Kim, YL Jin, HS Kim - Archives of pharmacal research, 2009 - Springer
Novel oxygen-incorporated SAHA (oxa-SAHA) analogues, in which oxygen was inserted in
the alkyl linker connecting the hydroxamic acid moiety and amide group, were synthesized …
the alkyl linker connecting the hydroxamic acid moiety and amide group, were synthesized …
Upregulation of Somatostatin Receptor Type 2 in a Receptor-Deficient In Vivo Pancreatic Neuroendocrine Tumor Model Improves Tumor Response to Targeted 177 …
R Sharma, B Earla, K Baidoo, MA Zeiger, JP Madigan… - bioRxiv, 2022 - biorxiv.org
Purpose The goal of this study was to test whether histone deacetylase inhibitors (HDACis)
restore somatostatin receptor type 2 (SSTR2) expression in models of high-grade pancreatic …
restore somatostatin receptor type 2 (SSTR2) expression in models of high-grade pancreatic …