In a European BIOMED-2 collaborative study, multiplex PCR assays have successfully been
developed and standardized for the detection of clonally rearranged immunoglobulin (Ig) …

Chimerism analysis has become an important tool for the peri-transplant surveillance of
engraftment. It offers the possibility to realize impending graft rejection and can serve as an …

Most modern treatment protocols for acute lymphoblastic leukaemia (ALL) include the
analysis of minimal residual disease (MRD). To ensure comparable MRD results between …

Chimeric antigen receptor‐modified T‐cell (CAR‐T) therapy is effective and safe for patients
with relapsed/refractory B‐cell acute lymphoblastic leukemia (r/r B‐ALL), but its value has …

Purpose Minimal residual disease (MRD) before allogeneic stem-cell transplantation was
shown to predict outcome in children with relapsed acute lymphoblastic leukemia (ALL) in …

Acute lymphoblastic leukaemia (ALL) is the most common childhood cancer. Treatment has
improved but relapsed ALL remains more common than new cases of many …

Purpose Treatment of childhood relapsed acute lymphoblastic leukemia (ALL) remains a
significant challenge. The goal of the Children's Oncology Group (COG) AALL01P2 study …

Aim Outcomes of children with high-risk (HR) relapsed acute lymphoblastic leukaemia
(ALL)(N= 393), recruited to ALLR3 and ALL-REZ BFM 2002 trials, were analysed. Minimal …

We report on posttransplant relapsed pediatric patients with B-precursor acute lymphoblastic
leukemia with no further standard of care therapy who were treated with the T-cell engaging …

Monitoring of Minimal Residual Disease After Allogeneic Stem-Cell Transplantation in
Relapsed Childhood Acute Lymphoblastic Leuk Page 1 Monitoring of Minimal Residual …