Bacterial antibiotic resistance: The most critical pathogens

G Mancuso, A Midiri, E Gerace, C Biondo - Pathogens, 2021 - mdpi.com
Antibiotics have made it possible to treat bacterial infections such as meningitis and
bacteraemia that, prior to their introduction, were untreatable and consequently fatal …

Emerging Carbapenem-Resistant Enterobacteriaceae Infection, Its Epidemiology and Novel Treatment Options: A Review

M Tilahun, Y Kassa, A Gedefie… - Infection and drug …, 2021 - Taylor & Francis
Infections due to multidrug-resistant Enterobacteriaceae have become major international
public health problem due to the inadequate treatment options and the historically lagged …

Treatment options for K. pneumoniae, P. aeruginosa and A. baumannii co-resistant to carbapenems, aminoglycosides, polymyxins and tigecycline: an approach …

S Karakonstantis, EI Kritsotakis, A Gikas - Infection, 2020 - Springer
The management of carbapenem-resistant infections is often based on polymyxins,
tigecycline, aminoglycosides and their combinations. However, in a recent systematic …

Tetracyclines and bone: Unclear actions with potentially lasting effects

AJ Warner, JD Hathaway-Schrader, R Lubker… - Bone, 2022 - Elsevier
Tetracyclines are a broad-spectrum class of antibiotics that have unclear actions with
potentially lasting effects on bone metabolism. Initially isolated from Streptomyces …

Impact of oxytetracycline on anaerobic wastewater treatment and mitigation using enhanced hydrolysis pretreatment

Y He, Z Tian, Q Yi, Y Zhang, M Yang - Water Research, 2020 - Elsevier
In this study, two parallel-operated up-flow anaerobic sludge bed reactors, one used to treat
synthetic wastewater spiked with oxytetracycline and the other used to treat the same …

Fosfomycin as partner drug for systemic infection management. A systematic review of its synergistic properties from in vitro and in vivo studies

RM Antonello, L Principe, AE Maraolo, V Viaggi, R Pol… - Antibiotics, 2020 - mdpi.com
Fosfomycin is being increasingly prescribed for multidrug-resistant bacterial infections. In
patients with systemic involvement, intravenous fosfomycin is usually administered as a …

Layered biocompatible pH-responsive antibacterial composite film based on HNT/PLGA/chitosan for controlled release of minocycline as burn wound dressing

A Mohebali, M Abdouss - International journal of biological …, 2020 - Elsevier
In the present study, a promising pH-responsive wound dressing was prepared. Halloysite
nanotube (HNT) composites were modified with different concentration of both poly (lactic-co …

Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens

N Dillon, M Holland, H Tsunemoto, B Hancock… - …, 2019 - thelancet.com
Abstract Background Multidrug-resistant (MDR) Acinetobacter baumannii infections have
high mortality rates and few treatment options. Synergistic drug combinations may improve …

[HTML][HTML] Minocycline, focus on mechanisms of resistance, antibacterial activity, and clinical effectiveness: Back to the future

A Asadi, M Abdi, E Kouhsari, P Panahi… - Journal of global …, 2020 - Elsevier
Objectives The increasing crisis regarding multidrug-resistant (MDR) and extensively drug-
resistant microorganisms leads to appealing therapeutic options. Methods During the last 30 …

[HTML][HTML] Molecular epidemiology of multidrug-resistant Klebsiella pneumoniae isolates in a Brazilian tertiary hospital

JK Palmeiro, RF De Souza, MA Schörner… - Frontiers in …, 2019 - frontiersin.org
Multidrug-resistant (MDR) Klebsiella pneumoniae (Kp) is a major bacterial pathogen
responsible for hospital outbreaks worldwide, mainly via the spread of high-risk clones and …