IL-32 is the name given to the NK4 transcript first reported in IL-2 activated T lymphocytes
and natural killer cells 13 years ago without known function. The novel cytokine has six …

Sensitizations to house dust mites (HDM) trigger strong exacerbated allergen‐induced
inflammation of the skin and airways mucosa from atopic subjects resulting in atopic …

Early life stress is a predisposing factor for the development of chronic intestinal disorders in
adult life. Here, we show that stress associated with early weaning in pigs leads to impaired …

IL-32, a recently discovered proinflammatory cytokine with four isoforms, induces IL-1β, TNF-
α, IL-6, and chemokines. Here, we used ligand (IL-32α) affinity chromatography in an …

Ion transport is essential for maintenance of transmembranous and transcellular electric
potential, fluid transport and cellular volume. Disturbance of ion transport has been …

Background Proteinase‐activated receptor 2 (PAR 2) is a G protein‐coupled receptor
activated by trypsin‐like serine proteinases. PAR 2 activation has been associated with …

Multiple K+ channels are expressed in the respiratory epithelium lining airways and alveoli.
Of the three main classes [1) voltage-dependent or Ca2+-activated, 6-transmembrane …

Protease activity is a characteristic common to many allergens. Allergen source‐derived
proteases interact with lung epithelial cells, which are now thought to play vital roles in both …

Inhalation of the fungus Alternaria alternata is associated with an increased risk of allergic
asthma development and exacerbations. Recent work in acute exposure animal models …

Type 2 inflammation in asthma develops with exposure to stimuli to include inhaled
allergens from house dust mites (HDM). Features include mucus hypersecretion and the …