Inflammatory bowel disease in pregnancy and breastfeeding

MN Brondfield, U Mahadevan - Nature Reviews Gastroenterology & …, 2023 - nature.com
Inflammatory bowel disease (IBD) has a peak age of diagnosis before the age of 35 years.
Concerns about infertility, adverse pregnancy outcomes, and heritability of IBD have …

[HTML][HTML] Pregnancy and autoimmune disease: diseases of the nervous system, connective tissue, and the bowel

WM Merz, R Fischer-Betz, K Hellwig… - Deutsches Ärzteblatt …, 2022 - ncbi.nlm.nih.gov
Background Pregnancies in women with chronic disease are on the rise. This pertains to
autoimmune diseases in particular since these tend to affect women of childbearing age …

European Crohn's and colitis guidelines on sexuality, fertility, pregnancy, and lactation

J Torres, M Chaparro, M Julsgaard… - Journal of Crohn's …, 2023 - academic.oup.com
2. Methods This document represents the third version of the European Consensus on
reproduction in IBD. The development of this Consensus included the formulation of …

Aktualisierte S3-Leitlinie „Diagnostik und Therapie des Morbus Crohn “der Deutschen Gesellschaft für Gastroenterologie, Verdauungs-und Stoffwechselkrankheiten …

A Sturm, R Atreya, D Bettenworth… - Zeitschrift für …, 2022 - thieme-connect.com
Im Jahr 2019 wurden etwa 25 500 Patient* innen mit M. Crohn im Krankenhaus stationär
behandelt [1]. Meistens tritt die Erkrankung in der Adoleszenz und im jungen …

Positioning filgotinib in the treatment algorithm of moderate to severe ulcerative colitis

F D'Amico, F Magro, L Peyrin-Biroulet… - Journal of Crohn's and …, 2022 - academic.oup.com
Abstract Background and Aims Filgotinib is a small molecule that selectively inhibits Janus
kinase [JAK] type 1. It is already approved for the treatment of rheumatoid arthritis and is …

Predictors of disease activity during pregnancy in women with inflammatory bowel disease—A Danish cohort study

T Vestergaard, M Julsgaard, JF Røsok… - Alimentary …, 2023 - Wiley Online Library
Summary Background and Aims Inflammatory bowel disease (IBD) activity during pregnancy
is associated with adverse pregnancy outcomes. We aimed to identify key clinical …

Exposure to corticosteroids in pregnancy is associated with adverse perinatal outcomes among infants of mothers with inflammatory bowel disease: results from the …

FD Odufalu, M Long, K Lin, U Mahadevan - Gut, 2022 - gut.bmj.com
Objective Active inflammatory bowel disease (IBD) during pregnancy may require the use of
corticosteroids. The aim of this study was to investigate the impact of in utero corticosteroid …

Benefits and risks associated with continuation of anti–tumor necrosis factor after 24 weeks of pregnancy in women with inflammatory bowel disease: a nationwide …

A Meyer, A Neumann, J Drouin, A Weill… - Annals of Internal …, 2022 - acpjournals.org
Background: Continuation of biologics for inflammatory disorders during pregnancy is still a
difficult decision. Many women with inflammatory bowel diseases (IBDs) stop anti–tumor …

Immunological effects and safety of live rotavirus vaccination after antenatal exposure to immunomodulatory biologic agents: a prospective cohort study from the …

T Fitzpatrick, K Alsager, M Sadarangani… - The Lancet Child & …, 2023 - thelancet.com
Background People with inflammatory or autoimmune diseases are recommended to
continue immunomodulatory biologic agents throughout pregnancy. However, concerns …

[HTML][HTML] Management of non-response and loss of response to anti-tumor necrosis factor therapy in inflammatory bowel disease

J Marsal, M Barreiro-de Acosta, I Blumenstein… - Frontiers in …, 2022 - frontiersin.org
Anti-TNF therapy has been successfully used as first-line biologic treatment for moderate-to-
severe inflammatory bowel disease (IBD), in both 'step-up'and 'top-down'approaches, and …