Targeted therapy for advanced thyroid cancer: kinase inhibitors and beyond

ME Cabanillas, M Ryder, C Jimenez - Endocrine reviews, 2019 - academic.oup.com
The treatment of advanced thyroid cancer has undergone rapid evolution in the last decade,
with multiple kinase inhibitor drug approvals for each subtype of thyroid cancer and a …

Thyroid nodules

G Popoveniuc, J Jonklaas - Medical Clinics of North America, 2012 - Elsevier
Thyroid nodules are common entities, clinically important primarily because of their
malignant potential. Serum thyrotropin and thyroid ultrasonography are pivotal in evaluating …

Phase II study of daily sunitinib in FDG-PET–positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional …

LL Carr, DA Mankoff, BH Goulart, KD Eaton… - Clinical Cancer …, 2010 - AACR
Purpose: We conducted a phase II study to assess the efficacy of continuous dosing of
sunitinib in patients with flurodeoxyglucose positron emission tomography (FDG-PET)–avid …

Detection rate of FNA cytology in medullary thyroid carcinoma: a meta‐analysis

P Trimboli, G Treglia, L Guidobaldi… - Clinical …, 2015 - Wiley Online Library
Background The early detection of medullary thyroid carcinoma (MTC) can improve patient
prognosis, because histological stage and patient age at diagnosis are highly relevant …

[HTML][HTML] Novel targeted therapies for metastatic thyroid cancer—a comprehensive review

M Al-Jundi, S Thakur, S Gubbi, J Klubo-Gwiezdzinska - Cancers, 2020 - mdpi.com
The knowledge on thyroid cancer biology has grown over the past decade. Thus, diagnostic
and therapeutic strategies to manage thyroid cancer are rapidly evolving. With new insights …

Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalities

E Resmini, F Minuto, A Colao, D Ferone - Acta diabetologica, 2009 - Springer
The secondary occurrence of type 2 diabetes with various hormonal diseases (eg pituitary,
adrenal and/or thyroid diseases) is a recurrent observation. Indeed, impaired glucose …

Targeting the RET Pathway in Thyroid Cancer

SA Wells Jr, M Santoro - Clinical Cancer Research, 2009 - AACR
The RET (rearranged during transfection) protooncogene encodes a single pass
transmembrane receptor that is expressed in cells derived from the neural crest and the …

Drosophila cancer models

VA Rudrapatna, RL Cagan, TK Das - Developmental Dynamics, 2012 - Wiley Online Library
Cancer is driven by complex genetic and cellular mechanisms. Recently, the Drosophila
community has become increasingly interested in exploring cancer issues. The Drosophila …

Management of medullary thyroid carcinoma and MEN2 syndromes in childhood

SG Waguespack, TA Rich, ND Perrier… - Nature Reviews …, 2011 - nature.com
Medullary thyroid carcinoma (MTC) and the multiple endocrine neoplasia (MEN) type 2
syndromes are rare but important endocrine diseases that are increasingly managed by …

Update on the cytologic and molecular features of medullary thyroid carcinoma

MP Pusztaszeri, M Bongiovanni… - Advances in Anatomic …, 2014 - journals.lww.com
Medullary thyroid carcinoma (MTC) accounts for only 5% to 10% of all thyroid carcinomas,
but it is the most aggressive form of well-differentiated thyroid carcinoma, being responsible …