Tissue homeostasis and inflammation
ML Meizlish, RA Franklin, X Zhou… - Annual review of …, 2021 - annualreviews.org
There is a growing interest in understanding tissue organization, homeostasis, and
inflammation. However, despite an abundance of data, the organizing principles of tissue …
inflammation. However, despite an abundance of data, the organizing principles of tissue …
Nanoparticle toxicology
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression
Glioblastoma (GBM), a highly lethal brain cancer, is notorious for immunosuppression, but
the mechanisms remain unclear. Here, we documented a temporospatial patterning of tumor …
the mechanisms remain unclear. Here, we documented a temporospatial patterning of tumor …
Hypoxia-modified cancer cell metabolism
W Al Tameemi, TP Dale, RMK Al-Jumaily… - Frontiers in cell and …, 2019 - frontiersin.org
While oxygen is critical to the continued existence of complex organisms, extreme levels of
oxygen within a system, known as hypoxia (low levels of oxygen) and hyperoxia (excessive …
oxygen within a system, known as hypoxia (low levels of oxygen) and hyperoxia (excessive …
Hypoxia: overview on hypoxia-mediated mechanisms with a focus on the role of HIF genes
AA Tirpe, D Gulei, SM Ciortea, C Crivii… - International journal of …, 2019 - mdpi.com
Hypoxia represents a frequent player in a number of malignancies, contributing to the
development of the neoplastic disease. This review will discuss the means by which hypoxia …
development of the neoplastic disease. This review will discuss the means by which hypoxia …
In situ forming injectable hydrogels for drug delivery and wound repair
R Dimatteo, NJ Darling, T Segura - Advanced drug delivery reviews, 2018 - Elsevier
Hydrogels have been utilized in regenerative applications for many decades because of
their biocompatibility and similarity in structure to the native extracellular matrix. Initially …
their biocompatibility and similarity in structure to the native extracellular matrix. Initially …
Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects
M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
Scaffold-free cell-based tissue engineering therapies: advances, shortfalls and forecast
Cell-based scaffold-free therapies seek to develop in vitro organotypic three-dimensional
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …
Metabolic reprogramming in clear cell renal cell carcinoma
HI Wettersten, OA Aboud, PN Lara Jr… - Nature Reviews …, 2017 - nature.com
Research in many cancers has uncovered changes in metabolic pathways that control
tumour energetics and biosynthesis, so-called metabolic reprogramming. Studies in clear …
tumour energetics and biosynthesis, so-called metabolic reprogramming. Studies in clear …
Oxygen-Deficient Tungsten Oxide (WOx) Nanobelts with pH-Sensitive Degradation for Enhanced Sonodynamic Therapy of Cancer
The further bioapplications of sonodynamic therapy (SDT) were hindered by the inadequate
efficiency and poor degradability of sonosensitizers and the hypoxic tumor …
efficiency and poor degradability of sonosensitizers and the hypoxic tumor …