Although reported in the literature, ribosome heterogeneity is a phenomenon whose extent
and implications in cell and organismal biology is not fully appreciated. This has been the …

Osteoporosis (OP) is a prevalent age-related disease that is characterized by a decrease in
bone mineral density (BMD) and systemic bone microarchitectural disorders. With age …

Introduction Neuropilin 2 (NRP2) mediates the effects of class 3 semaphorins and vascular
endothelial growth factor and is implicated in axonal guidance and angiogenesis. Moreover …

Y-box binding protein 1 (YBX1), a member of the Cold Shock Domain protein family, is
overexpressed in various human cancers and is recognized as an oncogenic gene …

Osteoporosis is a prevalent chronic metabolic bone disease that poses a significant risk of
fractures or mortality in elderly individuals. Its pathophysiological basis is often attributed to …

Background The vast majority of lncRNAs have low expression abundance, which greatly
limits their functional range and impact. As a high expression abundance lncRNA, FGD5 …

RNA-binding proteins (RBPs) interact with RNA and ubiquitously regulate RNA transcripts
during their life cycle, playing a fundamental role in the progression of angiogenesis-related …

Proteasome activator subunit 3 (PA28γ) is a member of the proteasome activator family,
which mainly regulates the degradation and stability of proteins. Studies have shown that it …

Alternative splicing is a crucial regulator in stem cell biology, intricately influencing the
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …

Exposure of articular cartilage to excessive mechanical loading is closely related to the
pathogenesis of osteoarthritis (OA). However, the exact molecular mechanism by which …