Harnessing human microbiomes for disease prediction

Y Liu, M Fachrul, M Inouye, G Méric - Trends in microbiology, 2024 - cell.com
The human microbiome has been increasingly recognized as having potential use for
disease prediction. Predicting the risk, progression, and severity of diseases holds promise …

Prognostic biomarkers based on proteomic technology in COPD: a recent review

H Fang, Y Liu, Q Yang, S Han… - International Journal of …, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a common heterogeneous respiratory
disease which is characterized by persistent and incompletely reversible airflow limitation …

Lower Airway Dysbiosis Augments Lung Inflammatory Injury in Mild-to-Moderate Chronic Obstructive Pulmonary Disease

I Sulaiman, BG Wu, M Chung, B Isaacs… - American Journal of …, 2023 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is associated with high morbidity,
mortality, and healthcare costs. Cigarette smoke is a causative factor; however, not all heavy …

[HTML][HTML] The application of multi-omics in the respiratory microbiome: Progresses, challenges and promises

J Gao, X Yi, Z Wang - Computational and Structural Biotechnology Journal, 2023 - Elsevier
The study of the respiratory microbiome has entered a multi-omic era. Through integrating
different omic data types such as metagenome, metatranscriptome, metaproteome …

Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease

J Gao, Y Yang, X Xiang, H Zheng, X Yi, F Wang… - Respiratory …, 2024 - Springer
Little is known about the relationships between human genetics and the airway microbiome.
Deeply sequenced airway metagenomics, by simultaneously characterizing the microbiome …

[HTML][HTML] Correcting dysbiosis in the lungs of COPD, one pathogen at a time

KK Wong, LN Segal - Cell Host & Microbe, 2023 - Elsevier
In this issue of Cell Host & Microbe, Liang et al. demonstrate through genomic analysis of
the sputum microbiome from COPD patients and preclinical models that Staphylococcus …

The translational potential of the lung microbiome as a biomarker and a therapeutic target for chronic obstructive pulmonary disease

L Yang, N Li, X Yi, Z Wang - Interdisciplinary Medicine, 2023 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major chronic lung disease with a
leading global morbidity and mortality. Emerging evidence suggests that the lung …

The Lung Microbiome

JH Lipinksi, P Ranjan, RP Dickson… - The Journal of …, 2024 - journals.aai.org
Although the lungs were once considered a sterile environment, advances in sequencing
technology have revealed dynamic, low-biomass communities in the respiratory tract, even …

Stenotrophomonas maltophilia contributes to smoking-related emphysema through IRF1-triggered PANoptosis of alveolar epithelial cells

H Xia, J Lin, Y Wang, J Yu, H Wang, C Cheng… - Environmental …, 2024 - Elsevier
Cigarette smoke (CS), the main source of indoor air pollution and the primary risk factor for
respiratory diseases, contains chemicals that can perturb microbiota through antibiotic …

ERS International Congress 2023: highlights from the Respiratory Infections Assembly

F Bindo, G Fumagalli… - ERJ Open …, 2024 - Eur Respiratory Soc
The 2023 European Respiratory Society Congress took place on a hybrid platform, with
participants joining online and in-person in Milan, Italy. The congress welcomed over 20 000 …