This study aimed to investigate whether Actovegin, which is a deproteinized ultrafiltrate
derived from calf blood, demonstrates neuroprotective effects in a rat model of transient …

Backgorund: Oxidative stress is one of the main contributing factors involved in cerebral
biochemical impairment. The higher susceptibility of the central nervous system to reactive …

We measured changes in gene expression, induced by aging and caloric restriction (CR), in
three hippocampal subregions. When analysis included all regions, aging was associated …

Age-related brain iron accumulation is linked with oxidative stress, neurodegeneration and
cognitive decline. Certain nutrients can reduce brain iron concentration in animal models …

Transient ischemia and reperfusion selectively damage neurons in brain, with hippocampal
pyramidal cells being particularly vulnerable. Even within hippocampus, heterogeneous …

Aging in the brain is a multicellular process manifesting as neurodegeneration and
associated functional impairment. In the present study, we report that cerebellar granule …

Monosodium glutamate (MSG) is believed to exert deleterious effects on various organs,
including the hippocampus, likely via the oxidative stress pathway. Garlic (Alium sativum L.) …

Functional and structural age-associated changes in the blood-brain barrier (BBB) may
affect the neurovascular unit and contribute to the onset and progression of age-associated …

Brain ageing in mice leads to the progressive appearance and expansion of degenerative
granular structures frequently referred as “PAS granules” because of their positive staining …

Background and aim The adverse neurological effects of tramadol have recently raised
attention. The literature pertaining to studying postnatal cerebellar changes induced by …