Epidemiological studies show that adverse cardiovascular events peak in the morning (ie,
between 6 AM and noon) and that shift work is associated with cardiovascular disease …

Circadian and sleep‐homeostatic processes both contribute to sleep timing and sleep
structure. Elimination of circadian rhythms through lesions of the suprachiasmatic nuclei …

This review consolidates research employing human correlational and experimental work
across brain and body with experimental animal models to provide a more complete …

In mammals, the circadian and stress systems (both centers of which are located in the
hypothalamus) are involved in adaptation to predictable and unpredictable environmental …

Circadian rhythms regulate a wide variety of physiological and metabolic processes. The
clock machinery comprises complex transcriptional–translational feedback loops that …

The mammalian circadian clock system, which includes the master clock and peripheral
clocks, times different biological processes in reaction to external cues, such as the light …

Background & Aims: Based on observations that the gastrointestinal tract is subject to
various 24-hour rhythmic processes, it is conceivable that some of these rhythms are under …

Various peripheral tissues show circadian rhythmicity, which is generated at the cellular
level by their own core oscillators that are composed of transcriptional/translational feedback …

The last decade has seen tremendous progress in our understanding of the organization
and function of the circadian clock. A number of so‐called clock genes were discovered, and …

In mammals, daily rhythms in behaviour and physiology are driven by a circadian timing
system comprised, in a hierarchical way, of a master pacemaker in the suprachiasmatic …