Abstract Lotilaner ophthalmic solution 0.25%(XDEMVY™), a gamma-aminobutyric acid-
gated chloride channel (GABA-Cl) inhibitor selective for mites, is being developed by Tarsus …

Dry eye disease (DED) can arise from a variety of factors, including inflammation,
meibomian gland dysfunction (MGD), and neurosensory abnormalities. Individuals with DED …

This study aimed to investigate the impact of ocular demodicosis on dry eye disease (DED)
and meibomian gland dysfunction (MGD) across different age populations: young (20 to< …

Purpose This review aims to assess the safety and efficacy of Lotilaner in the treatment of
Demodex Blepharitis. Design Systematic Review and Meta-Analysis Background Demodex …

Purpose Demodex blepharitis, often overlooked in ocular surface disease, involves
Demodex mites, prevalent ectoparasites on human skin. Current treatments may not …

Purpose To evaluate the safety and efficacy of Lotilaner ophthalmic solution 0.25% in the
treatment of demodex blepharitis. Methods PubMed, Web of Science, Scopus, and Embase …

Demodex blepharitis is marked by an excessive presence of Demodex mites on the eyelids,
particularly in the lash follicles. While these microscopic mites are a natural component of …

Due to their relatively high prevalence and commensalism, the pathogenicity of Demodex
mites has been debated. Recent data, however, show Demodex to be associated with skin …

Purpose: The aim of this study was to report clinical observations suggesting the efficacy of
topical 1% 5-fluorouracil (5-FU) in treating Demodex-associated blepharitis. Methods: An …

Blepharitis Preferred Practice Pattern® Blepharitis Preferred Practice Pattern®
Ophthalmology. 2024 Feb 12:S0161-6420(24)00008-3. doi: 10.1016/j.ophtha.2023.12.036 …