Network medicine is an emerging area of research dealing with molecular and genetic
interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale …

Co-expression network analysis is one of the most powerful approaches for interpretation of
large transcriptomic datasets. It enables characterization of modules of co-expressed genes …

Monoterpene indole alkaloids (MIAs) are a structurally diverse family of specialized
metabolites mainly produced in Gentianales to cope with environmental challenges. Due to …

Unraveling gene function is pivotal to understanding the signaling cascades that control
plant development and stress responses. As experimental profiling is costly and labor …

The liverwort Marchantia polymorpha is equipped with a wide range of molecular and
genetic tools and resources that have led to its wide use to explore the evo-devo aspects of …

Highlights•GRNs represent causal relationships among regulators and their downstream
genes.•Biological hypothesis drives data collection and the subsequent inferred …

Diatoms are a diverse group of mainly photosynthetic algae, responsible for 20% of
worldwide oxygen production, which can rapidly respond to favorable conditions and often …

Summary Plant specialized 1, 4-naphthoquinones present a remarkable case of convergent
evolution. Species across multiple discrete orders of vascular plants produce diverse 1, 4 …

Elucidating plant-specialized biosynthetic pathways has always constituted a laborious task,
notably for natural products with high pharmaceutical values. Here, we discuss emerging …

In this study, we investigated cancer cellular networks in the context of gene interactions and
their associated patterns in order to recognize the structural features underlying this disease …