[HTML][HTML] Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment
Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
Gene editing and CRISPR in the clinic: current and future perspectives
Genome editing technologies, particularly those based on zinc-finger nucleases (ZFNs),
transcription activator-like effector nucleases (TALENs), and CRISPR (clustered regularly …
transcription activator-like effector nucleases (TALENs), and CRISPR (clustered regularly …
Delivery of CRISPR/Cas systems for cancer gene therapy and immunotherapy
The clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-
associated protein (Cas) systems are efficient and versatile gene editing tools, which offer …
associated protein (Cas) systems are efficient and versatile gene editing tools, which offer …
Engineering cell membrane‐based nanotherapeutics to target inflammation
Inflammation is ubiquitous in the body, triggering desirable immune response to defend
against dangerous signals or instigating undesirable damage to cells and tissues to cause …
against dangerous signals or instigating undesirable damage to cells and tissues to cause …
Non-viral delivery of the CRISPR/Cas system: DNA versus RNA versus RNP
Since its discovery, the CRISPR/Cas technology has rapidly become an essential tool in
modern biomedical research. The opportunities to specifically modify and correct genomic …
modern biomedical research. The opportunities to specifically modify and correct genomic …
Engineered materials for in vivo delivery of genome-editing machinery
Genome-editing technologies, such as CRISPR–Cas9, are promising for treating otherwise
incurable genetic diseases. Great progress has been made for ex vivo genome editing; …
incurable genetic diseases. Great progress has been made for ex vivo genome editing; …
Rational designs of in vivo CRISPR-Cas delivery systems
The CRISPR-Cas system initiated a revolution in genome editing when it was, for the first
time, demonstrated success in the mammalian cells. Today, scientists are able to readily edit …
time, demonstrated success in the mammalian cells. Today, scientists are able to readily edit …
Engineered nanomaterials to potentiate CRISPR/Cas9 gene editing for cancer therapy
Clustered regularly interspaced short palindromic repeats/associated protein 9
(CRISPR/Cas9) gene‐editing technology shows promise for manipulating single or multiple …
(CRISPR/Cas9) gene‐editing technology shows promise for manipulating single or multiple …
Delivery of CRISPR/Cas9 for therapeutic genome editing
The clustered, regularly‐interspaced, short palindromic repeat (CRISPR)‐associated
nuclease 9 (CRISPR/Cas9) is emerging as a promising genome‐editing tool for treating …
nuclease 9 (CRISPR/Cas9) is emerging as a promising genome‐editing tool for treating …
Delivery systems for nucleic acids and proteins: Barriers, cell capture pathways and nanocarriers
Gene therapy has been used as a potential approach to address the diagnosis and
treatment of genetic diseases and inherited disorders. In this line, non-viral systems have …
treatment of genetic diseases and inherited disorders. In this line, non-viral systems have …