The molecular mechanism of Nrf2-Keap1 signaling pathway in the antioxidant defense response induced by BaP in the scallop Chlamys farreri

H Wang, L Pan, R Xu, L Si, X Zhang - Fish & Shellfish Immunology, 2019 - Elsevier
In this study, we cloned the full-length cDNA of the Kelch-like ECH-associated protein 1
(Keap1) from the scallops Chlamys farreri (C. farreri). Sequences alignment and …

Redox control of antioxidants, metabolism, immunity, and development at the core of stress adaptation of the oyster Crassostrea gigas to the dynamic intertidal …

R Trevisan, DF Mello - Free Radical Biology and Medicine, 2023 - Elsevier
This review uses the marine bivalve Crassostrea gigas to highlight redox reactions and
control systems in species living in dynamic intertidal environments. Intertidal species face …

MitoQ ameliorates testis injury from oxidative attack by repairing mitochondria and promoting the Keap1-Nrf2 pathway

J Zhang, X Bao, M Zhang, Z Zhu, L Zhou… - Toxicology and applied …, 2019 - Elsevier
Mitochondrial dysfunctions induced by oxidative stress could play a pivotal role in the
development of testicular damage and degeneration, leading to impaired fertility in …

[HTML][HTML] Toxic Responses of Different Shellfish Species after Exposure to Prorocentrum lima, a DSP Toxins Producing Dinoflagellate

MH Ye, DW Li, QD Cai, YH Jiao, Y Liu, HY Li, WD Yang - Toxins, 2022 - mdpi.com
Prorocentrum lima is a global benthic dinoflagellate that produces diarrhetic shellfish
poisoning (DSP) toxins, which can be ingested by filter-feeding bivalves, and eventually …

Effects of dietary lipid levels on growth performance, hepatic health, lipid metabolism and intestinal microbiota on Trachinotus ovatus

HH Fang, W Zhao, JJ Xie, P Yin, ZX Zhuang… - Aquaculture …, 2021 - Wiley Online Library
Proper dietary lipid is beneficial for the protein‐sparing effect and reduces feed budget.
Therefore, 8 weeks trial feeding with different lipid levels diets was performed to determine …

[HTML][HTML] Cold exposure induced oxidative stress and apoptosis in the myocardium by inhibiting the Nrf2-Keap1 signaling pathway

P Cong, Y Liu, N Liu, Y Zhang, C Tong, L Shi… - BMC Cardiovascular …, 2018 - Springer
Background Exposure to cold weather is associated with infaust cardiovascular responses,
including myocardial infarction and arrhythmias. However, the exact mechanisms of these …

Atorvastatin causes oxidative stress and alteration of lipid metabolism in estuarine goby Mugilogobius abei

Y Wang, C Wang, M Xie, T Tang, Z Wang, X Nie - Environmental Pollution, 2021 - Elsevier
The potential effects of the environmental residues of Atorvastatin (ATV) as a widely used
antilipemic agent on aquatic organisms deserve more investigations because of its high …

Identification of Nrf2/Keap1 pathway and its transcriptional regulation of antioxidant genes after exposure to microcystins in freshwater mussel Cristaria plicata

J Wu, W Liu, S Hou, Y Wang, H Fang, S Luo… - Developmental & …, 2023 - Elsevier
Microcystins (MC) are one of the most abundant and widely distributed cyanotoxins in
aquatic systems. MC inhibits the functions of protein phosphatase 1 and 2A (PP1/2A), which …

The Nrf2 molecule trigger antioxidant defense against acute benzo (a) pyrene exposure in the thick shell mussel Mytilus coruscus

P Qi, Z Tang - Aquatic Toxicology, 2020 - Elsevier
The NF-E2-related factor 2 (Nrf2), an ubiquitous, evolutionarily conserved transcription
factor, acts as a major sensor of oxidative stress in cells. In the present study, a Nrf2 …

Comparative biochemical and molecular responses of biotransformation and antioxidant systems in three species of Crassostrea (Sacco, 1897) oysters exposed to …

CLV Bastolla, D Lima, JJ Mattos, VHV Dias… - … and Physiology Part C …, 2023 - Elsevier
Chrysene (CHR) is among the most persistent polycyclic aromatic hydrocarbons (PAH) in
water and a priority compound for pollutants monitoring, due to its carcinogenic, mutagenic …