[HTML][HTML] Quantitative anti-HBc combined with quantitative HBsAg can predict HBsAg clearance in sequential combination therapy with PEG-IFN-α in NA-suppressed …

WX Wang, R Jia, YY Gao, JY Liu, JQ Luan… - Frontiers in …, 2022 - frontiersin.org
Background and aims Precise predictors are lacking for hepatitis B surface antigen (HBsAg)
clearance under the combination therapy of nucleos (t) ide analogs (NA) and pegylated …

Real‐world study on HBsAg loss of combination therapy in HBeAg‐negative chronic hepatitis B patients

JH Chu, Y Huang, DY Xie, H Deng, J Wei… - Journal of Viral …, 2022 - Wiley Online Library
Combination therapy with pegylated interferon (PEG‐IFN) and nucleos (t) ide analogues
(NAs) can enhance hepatitis B surface antigen (HBsAg) clearance. However, the specific …

Efficacy and safety of peginterferon alpha monotherapy in Chinese inactive chronic hepatitis B virus carriers

F Wu, R Lu, Y Liu, Y Wang, Y Tian, Y Li, M Li… - Liver …, 2021 - Wiley Online Library
Abstract Background & Aims The effectiveness and safety of peginterferon alpha (peg‐IFN‐
α) monotherapy in inactive hepatitis B virus (HBV) carriers (IHCs) have not been fully …

[HTML][HTML] Quantitative hepatitis B core antibody and quantitative hepatitis B surface antigen: Novel viral biomarkers for chronic hepatitis B management

W Leowattana, P Leowattana… - World Journal of …, 2024 - ncbi.nlm.nih.gov
The management of hepatitis B virus (HBV) infection now involves regular and appropriate
monitoring of viral activity, disease progression, and treatment response. Traditional HBV …

[HTML][HTML] Predictors of HBsAg seroclearance in patients with chronic HBV infection treated with pegylated interferon-α: a systematic review and meta-analysis

S Jiang, S Guo, Y Huang, Y Yin, J Feng, H Zhou… - Hepatology …, 2024 - Springer
Background and aims The identification of reliable predictors for hepatitis B surface antigen
(HBsAg) seroclearance remains controversial. We aimed to summarize potential predictors …

[HTML][HTML] Serum cytokine change profile associated with HBsAg loss during combination therapy with PEG-IFN-α in NAs-suppressed chronic hepatitis B patients

WX Wang, R Jia, XY Jin, X Li, SN Zhou… - Frontiers in …, 2023 - frontiersin.org
Objective The aim of this study was to explore the profile of cytokine changes during the
combination therapy with pegylated interferon alpha (PEG-IFN-α) and its relationship with …

[HTML][HTML] Clinical cure induced by pegylated interferon α-2b in the advantaged population of chronic hepatitis B virus infection: a retrospective cohort study

C Wen, Y Wang, H Tian, Y Lei, Z Wang… - Frontiers in Cellular …, 2024 - frontiersin.org
Background Among the advantaged population with clinical cure of chronic hepatitis B,
chronic inactive hepatitis B virus carriers (IHCs) and nucleoside analog-experienced …

Early clinical efficacy of pegylated interferon treatment in patients with different phases of chronic HBV infection: A real‐world analysis

W Zhang, M Xing, W Sun, J Chen, N Xie… - Journal of Viral …, 2023 - Wiley Online Library
Although there are therapeutic advantages for hepatitis B virus (HBV) withpegylated
interferon alpha (peg‐IFNα) treatment compared with nucleos (t) ide analog (NAs) therapy …

[HTML][HTML] Interferon add-on therapy increased clinical cure significantly for interferon-experienced chronic hepatitis B patients with low HBsAg

X Yang, K Zhang, Q Xu, X Shu, Z Mo, D Xie… - Frontiers in …, 2022 - frontiersin.org
Currently, interferon add-on therapy brings hope for clinical cure of chronic hepatitis B
patients with low HBsAg. However, in clinical practice patients with poor responses to their …

[HTML][HTML] Efficacy of peginterferon alfa-2b in nucleoside analogue experienced patients with negative HBeAg and low HBsAg: A non-randomized clinical trial

J Chen, M Qi, XG Fan, XW Hu, CJ Liao, LY Long… - Infectious Diseases and …, 2021 - Springer
Introduction Hepatitis B surface antigen (HBsAg) clearance is the treatment goal for hepatitis
B e antigen (HBeAg)-negative patients with chronic hepatitis B (CHB). However, its rate is …