Cancer-associated fibroblasts: an emerging target against esophageal squamous cell carcinoma

L Qiu, J Yue, L Ding, Z Yin, K Zhang, H Zhang - Cancer letters, 2022 - Elsevier
Esophageal squamous cell carcinoma (ESCC) is one of the most common human
malignancies worldwide and is associated with high morbidity and mortality. More than 70 …

Exploring the therapeutic efficacy of crocetin in oncology: an evidence-based review

W Koch, A Wawruszak, W Kukula-Koch… - Naunyn-Schmiedeberg's …, 2024 - Springer
With cancer being a leading cause of death globally, there is an urgent need to improve
therapeutic strategies and identify effective chemotherapeutics. This study aims to highlight …

PD-L1-expressing cancer-associated fibroblasts induce tumor immunosuppression and contribute to poor clinical outcome in esophageal cancer

K Kawasaki, K Noma, T Kato, T Ohara… - Cancer Immunology …, 2023 - Springer
The programmed cell death 1 protein (PD-1)/programmed cell death ligand 1 (PD-L1) axis
plays a crucial role in tumor immunosuppression, while the cancer-associated fibroblasts …

Cancer cell membrane fused liposomal platinum (iv) prodrugs overcome cisplatin resistance in esophageal squamous cell carcinoma chemotherapy

S Zhang, W Jiang, S Wang, K Song, M Ge… - Journal of Materials …, 2023 - pubs.rsc.org
Esophageal squamous cell carcinoma (ESCC) remains a major health challenge, with
cisplatin (CDDP) being the primary chemotherapy drug, albeit accompanied by resistance …

Circ_0001093 promotes glutamine metabolism and cancer progression of esophageal squamous cell carcinoma by targeting miR-579-3p/glutaminase axis

C Qian, Y Tong, Y Wang, X Teng, J Yao - Journal of Bioenergetics and …, 2022 - Springer
Increasing studies indicate that circular RNAs (circRNAs) play critical roles in tumor
metabolism of multiple cancers. However, the contribution of circRNAs in glutamine …

Development and validation of a machine learning model for survival risk stratification after esophageal cancer surgery

J Xu, J Zhou, J Hu, Q Ren, X Wang, Y Shu - Frontiers in Oncology, 2022 - frontiersin.org
Background Prediction of prognosis for patients with esophageal cancer (EC) is beneficial
for their postoperative clinical decision-making. This study's goal was to create a …

Applying Untargeted Lipidomics to Evaluate the Efficacy of Combined Neoadjuvant Chemotherapy and Immunotherapy for Esophageal Squamous Carcinoma …

W Lin, X Si, Z Zhao, F Chen, J Xu… - Journal of Proteome …, 2024 - ACS Publications
Esophageal squamous cell carcinoma (ESCC) is an aggressive malignant tumor with a poor
prognosis due to insidious symptoms that make early diagnosis difficult. Despite the …

Interleukin-8 and interleukin-6 are biomarkers of poor prognosis in esophageal squamous cell carcinoma

PRA Pastrez, AM Barbosa, VS Mariano, RL Causin… - Cancers, 2023 - mdpi.com
Simple Summary Esophageal squamous cell carcinoma (SCC) is an extremely aggressive
malignancy with high mortality rates. An important variable in understanding this …

HOXC10 promotes esophageal squamous cell carcinoma progression by targeting FOXA3 and indicates poor survival outcome

X He, H Wang, R Wang, Y Li, S Li, X Cao, J Xu - Heliyon, 2023 - cell.com
Background Esophageal cancer is one of the most unknown and deadliest cancers in the
world. Although recent studies have identified some mutations linked to the development of …

USP21-mediated G3BP1 stabilization accelerates proliferation and metastasis of esophageal squamous cell carcinoma via activating Wnt/β-Catenin signaling

J Guo, Y Zhao, H Sui, L Liu, F Liu, L Yang, F Gao… - Oncogenesis, 2024 - nature.com
Lacking effective therapeutic targets heavily restricts the improvement of clinical prognosis
for patients diagnosed with esophageal squamous cell carcinoma (ESCC). Ubiquitin …