Prostate cancer is the most prevalent cancer in males in Western countries. The reported
incidence in Asia is much lower than that in African Americans and European Caucasians …

The clinical use of genetic variation in the evaluation of cancer risk is expanding, and thus
understanding how determinants of cancer susceptibility identified in one population can be …

The enzyme steroid 5α-reductase (S5αR) catalyzes the conversion of Δ4-3-ketosteroid
precursors-such as testosterone, progesterone and androstenedione-into their 5α-reduced …

Androgens are an important class of C19 steroid hormones that control normal male
development and reproductive function. The main circulating androgen is testosterone …

OBJECTIVES: To assess the efficacy and safety of tubeless percutaneous nephrolithotomy
(PCNL) compared with standard or small-bore PCNL with a meta-analysis of randomized …

Prostate cancer is the leading non-skin malignancy detected in US males and the second
cause of death due to male cancer in the US. Androgenic hormones are generally believed …

Over the past decades, several studies have shown that tumor-related somatic and germline
alterations predicts tumor prognosis, drug response and toxicity. Latin American populations …

One hundred and forty‐six index patients with 46, XY DSD in whom gonads were confirmed
as testes were consecutively studied for a molecular diagnosis during the period 2002 …

Prostate cancer (PCa) is the most commonly diagnosed male malignancy and the second
biggest cause of cancer death in men of the Western world. Higher incidences of PCa occur …

Abstract The steroid-5-alpha-reductase, alpha polypeptide 2 (SRD5A2) gene plays a crucial
role in androgen metabolism pathway in human prostate. It encodes SRD5A2 enzyme …