Curcumin, a yellow pigment in the Indian spice Turmeric (Curcuma longa), which is
chemically known as diferuloylmethane, was first isolated exactly two centuries ago in 1815 …

Parkinson's disease (PD) is a slowly progressive multisystem disorder affecting
dopaminergic neurons of the substantia nigra pars compacta (SNpc), which is characterized …

Cancer remains a second leading cause of deaths and major public health problem. It
occurs due to extensive DNA damage caused by ultraviolet radiations, ionizing radiations …

The human genome encodes 538 protein kinases that transfer a γ-phosphate group from
ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

Introduction: Since ancient times, turmeric has been used in several folklore remedies
against various ailments. The principal component of turmeric is curcumin and its efficacy …

Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …

Background: Neovascularization, also known as angiogenesis, is the process of capillary
sprouting from pre-existing blood vessels. This physiological process is a hallmark event in …

Chrysin, a naturally occurring flavone, abundantly found in numerous plant extracts
including propolis and in honey is one of the most widely used herbal medicine in Asian …