Atherosclerosis and inflammation: Insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Nanoparticle-based drug delivery systems in cancer: A focus on inflammatory pathways

AR Afshari, M Sanati, H Mollazadeh… - Seminars in cancer …, 2022 - Elsevier
It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

The cytokine network in colorectal cancer: Implications for new treatment strategies

H Braumüller, B Mauerer, J Andris, C Berlin, T Wieder… - Cells, 2022 - mdpi.com
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only
limited therapeutic options. CRC is not only a genetic disease with several mutations in …

[HTML][HTML] Remodeling tumor microenvironment with natural products to overcome drug resistance

W Zhang, S Li, C Li, T Li, Y Huang - Frontiers in Immunology, 2022 - frontiersin.org
With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …

Genome editing via non-viral delivery platforms: current progress in personalized cancer therapy

T Lan, H Que, M Luo, X Zhao, X Wei - Molecular Cancer, 2022 - Springer
Cancer is a severe disease that substantially jeopardizes global health. Although
considerable efforts have been made to discover effective anti-cancer therapeutics, the …

Role of inflammatory mediators, macrophages, and neutrophils in glioma maintenance and progression: mechanistic understanding and potential therapeutic …

AS Basheer, F Abas, I Othman, R Naidu - Cancers, 2021 - mdpi.com
Simple Summary The tumor microenvironment is a complex network comprised of
neoplastic and a variety of immune cells, proteins, and inflammatory mediators. Previous …

Is depression the missing link between inflammatory mediators and cancer?

B Polityńska, O Pokorska, AM Wojtukiewicz… - Pharmacology & …, 2022 - Elsevier
Patients with cancer are at greater risk of developing depression in comparison to the
general population and this is associated with serious adverse effects, such as poorer …

Anti-Inflammatory and Antioxidant Effects of Carvacrol on N-Methyl-N′-Nitro-N-Nitrosoguanidine (MNNG) Induced Gastric Carcinogenesis in Wistar Rats

A Gunes-Bayir, EM Guler, MG Bilgin, IS Ergun… - Nutrients, 2022 - mdpi.com
Carvacrol is a dietary polyphenol from Lamiaceae plants that has been shown to possess a
wide range of biological activities including antioxidant and antitumor effects. This study …

Inflammatory cytokine: an attractive target for cancer treatment

HM Lee, HJ Lee, JE Chang - Biomedicines, 2022 - mdpi.com
The relationship between inflammation and cancer has attracted attention for a long time.
The inflammatory tumor microenvironment consists of inflammatory cells, chemokines …

Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer

A Lamsal, SB Andersen, I Johansson, M Vietri… - Cell Communication and …, 2023 - Springer
Background To our current understanding, solid tumors depend on suppressed local
immune reactions, often elicited by the interaction between tumor cells and tumor …