Gut microbiota and microbial metabolism in early risk of cardiometabolic disease
CL Gabriel, JF Ferguson - Circulation Research, 2023 - Am Heart Assoc
Cardiometabolic disease comprises cardiovascular and metabolic dysfunction and
underlies the leading causes of morbidity and mortality, both within the United States and …
underlies the leading causes of morbidity and mortality, both within the United States and …
The microbiome as a major function of the gastrointestinal tract and its implication in micronutrient metabolism and chronic diseases
D Lin, DM Medeiros - Nutrition Research, 2023 - Elsevier
The composition and function of microbes harbored in the human gastrointestinal lumen
have been underestimated for centuries because of the underdevelopment of nucleotide …
have been underestimated for centuries because of the underdevelopment of nucleotide …
[HTML][HTML] A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning
The gut microbiome has an important role in infant health and development. We
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …
The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota l-carnitine catabolism
JA Buffa, KA Romano, MF Copeland, DB Cody… - Nature …, 2022 - nature.com
The heightened cardiovascular disease (CVD) risk observed among omnivores is thought to
be linked, in part, to gut microbiota-dependent generation of trimethylamine-N-oxide (TMAO) …
be linked, in part, to gut microbiota-dependent generation of trimethylamine-N-oxide (TMAO) …
Atherosclerosis amelioration by allicin in raw garlic through gut microbiota and trimethylamine-N-oxide modulation
Cardiovascular disease (CVD) is strongly associated with the gut microbiota and its
metabolites, including trimethylamine-N-oxide (TMAO), formed from metaorganismal …
metabolites, including trimethylamine-N-oxide (TMAO), formed from metaorganismal …
Gut microbiome and metabolome profiling in Framingham heart study reveals cholesterol-metabolizing bacteria
C Li, M Stražar, AMT Mohamed, JA Pacheco… - Cell, 2024 - cell.com
Accumulating evidence suggests that cardiovascular disease (CVD) is associated with an
altered gut microbiome. Our understanding of the underlying mechanisms has been …
altered gut microbiome. Our understanding of the underlying mechanisms has been …
Implications of trimethylamine N-oxide (TMAO) and betaine in human health: beyond being osmoprotective compounds
Osmolytes are naturally occurring small molecular weight organic molecules, which are
accumulated in large amounts in all life forms to maintain the stability of cellular proteins and …
accumulated in large amounts in all life forms to maintain the stability of cellular proteins and …
Inactivation of the antidiabetic drug acarbose by human intestinal microbial-mediated degradation
J Tian, C Li, Z Dong, Y Yang, J Xing, P Yu, Y Xin… - Nature …, 2023 - nature.com
Drugs can be modified or degraded by the gut microbiota, which needs to be considered in
personalized therapy. The clinical efficacy of the antidiabetic drug acarbose, an inhibitor of α …
personalized therapy. The clinical efficacy of the antidiabetic drug acarbose, an inhibitor of α …
[HTML][HTML] Advances in the integration of metabolomics and metagenomics for human gut microbiome and their clinical applications
F Puig-Castellví, R Pacheco-Tapia, M Deslande… - TrAC Trends in …, 2023 - Elsevier
The human microbiome and its metabolic output play an important role in shaping human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …
health and disease. The host-microbe crosstalk is often characterised using metabolomics …
Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition
The essential role of gut microbiota in health and disease is well recognized, but the
biochemical details that underlie the beneficial impact remain largely undefined. To maintain …
biochemical details that underlie the beneficial impact remain largely undefined. To maintain …