Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

The skin is the outermost layer of the body with an extensive surface area of approximately
1· 8 m2, and is the first line of defence against a multitude of external pathogens and …

The extracellular matrix (ECM) is a complex network of macromolecules surrounding cells
providing structural support and stability to tissues. The understanding of the ECM and the …

Chronic low-grade inflammation is a common hallmark of the aging process and many age-
related diseases. There is substantial evidence that persistent inflammation is associated …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade proteins of the
extracellular matrix and the basement membrane. Thus, these enzymes regulate airway …

Alterations in the composition of the extracellular matrix (ECM) critically regulate the cellular
responses in tissue repair, remodeling, and fibrosis. After injury, proteolytic degradation of …

Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free
regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell …

Harnessing the inflammation and angiogenesis is extremely important in wound healing. In
this study, we developed bioactive elastin-based hydrogels which can recruit and modulate …

Extracellular matrix (ECM) proteins confer biomechanical properties, maintain cell
phenotype and mediate tissue repair (via release of sequestered cytokines and proteases) …

Vitamin D is the first item of drug expenditure for the treatment of osteoporosis. Its deficiency
is a condition that affects not only older individuals but also young people. Recently, the …