Monoclonal antibodies constitute a promising class of targeted anticancer agents that
enhance natural immune system functions to suppress cancer cell activity and eliminate …

Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Antibody–drug conjugates (ADCs) are novel drugs that exploit the specificity of a
monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the …

Chimeric antigen receptor (CAR) T‐cell therapy represents a major advancement in
personalized cancer treatment. In this strategy, a patient's own T cells are genetically …

Proteolysis targeting chimera (PROTAC), hijacking protein of interest (POI) and recruiting E3
ligase for target degradation via the ubiquitin-proteasome pathway, is a novel drug …

Occupational, residential, dietary and environmental exposures to mixtures of synthetic
anthropogenic chemicals after World War II have a strong relationship with the increase of …

Trogocytosis is an active process, in which one cell extracts the cell fragment from another
cell, leading to the transfer of cell surface molecules, together with membrane fragments …

Cancer and autoimmune disease are closely related, and many therapeutic antibodies are
widely used in clinics for the treatment of both diseases. Among them, the anti-CD20 …

Abstract Cluster of differentiation 40 (CD40) mediates many immune activities. Preclinical
studies have shown that activation of CD40 can evoke massive antineoplastic effects in …

Monoclonal antibodies (mAbs) have been used in the development of immunotherapies that
target a variety of diseases, such as cancer, autoimmune diseases, and even viral infections; …