Background Achieving polio eradication requires ensuring the delivery of sufficient supplies
of the right vaccines to the right places at the right times. Despite large global markets …

Background Despite multiple revisions of targets and timelines in polio eradication plans
since 1988, including changes in supplemental immunization activities (SIAs) that increase …

Summary Background Between 2018 and 2022, Nigeria experienced continuous
transmission of circulating vaccine-derived type 2 poliovirus (cVDPV2), with 526 cases of …

Background The novel oral poliovirus vaccine type 2 (nOPV2) is now authorised by a WHO
emergency use listing and widely distributed to interrupt outbreaks of circulating vaccine …

Delays in achieving polio eradication have led to ongoing risks of poliovirus importations
that may cause outbreaks in polio-free countries. Because of the low, but non-zero risk of …

The Global Polio Eradication Initiative owes much of its success in vastly reducing wild
poliovirus transmission globally to the use of live-attenuated Sabin oral poliovirus vaccine …

A sharp rise in circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks in the years
following the cessation of routine use of poliovirus type 2-containing oral polio vaccine and …

Background Novel oral poliovirus vaccine (OPV) type 2 (nOPV2) has been made available
for outbreak response under an emergency use listing authorization based on supportive …

Poliomyelitis, a debilitating disease, has been largely eliminated due to the global
dissemination of effective vaccines. The first vaccine against poliovirus, introduced in 1961 …

Polio vaccines: hope, hype, and history repeating? Page 1 Polio vaccines: hope, hype, and
history repeating? Announcement of new polio vaccines has once again raised hopes of …