Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Stem cells can be defined as units of biological organization that are responsible for the
development and the regeneration of organ and tissue systems. They are able to renew their …

Mesenchymal stem cells are culture-derived mesodermal progenitors isolatable from all
vascularized tissues. In spite of multiple fundamental, pre-clinical and clinical studies, the …

Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

Adult stem cells that are tightly regulated by the specific microenvironment, or the stem cell
niche, function to maintain tissue homeostasis and regeneration after damage. This …

Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …

Mesenchymal stem/stromal cells (MSC) remain a promising tool for regenerative medicine
as the efficacy of MSC-based cell therapy has been demonstrated for a broad spectrum of …

Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

Extracellular matrix (ECM) provides both structural support and dynamic microenvironment
for cells regulating their behavior and fate. As a critical component of stem cell niche ECM …

Mesenchymal stem cell secretome or conditioned medium (MSC-CM) is a combination of
biomolecules and growth factors in cell culture growth medium, secreted by mesenchymal …