The pharmacokinetics and the pharmacodynamics of cannabinoids
CJ Lucas, P Galettis, J Schneider - British journal of clinical …, 2018 - Wiley Online Library
There is increasing interest in the use of cannabinoids for disease and symptom
management, but limited information available regarding their pharmacokinetics and …
management, but limited information available regarding their pharmacokinetics and …
Practical considerations in medical cannabis administration and dosing
CA MacCallum, EB Russo - European journal of internal medicine, 2018 - Elsevier
Cannabis has been employed medicinally throughout history, but its recent legal prohibition,
biochemical complexity and variability, quality control issues, previous dearth of …
biochemical complexity and variability, quality control issues, previous dearth of …
Towards better delivery of cannabidiol (CBD)
SA Millar, RF Maguire, AS Yates, SE O'Sullivan - Pharmaceuticals, 2020 - mdpi.com
Cannabidiol (CBD) has substantial therapeutic potential, but its development as an effective
drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low …
drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low …
A phase I, randomized, double-blind, placebo-controlled, single ascending dose, multiple dose, and food effect trial of the safety, tolerability and pharmacokinetics of …
L Taylor, B Gidal, G Blakey, B Tayo, G Morrison - CNS drugs, 2018 - Springer
Background A formal single ascending and multiple dose pharmacokinetic (PK) trial of
cannabidiol (CBD) oral solution was required to determine the safety and tolerability of CBD …
cannabidiol (CBD) oral solution was required to determine the safety and tolerability of CBD …
Interactions between cannabidiol and commonly used antiepileptic drugs
TE Gaston, EM Bebin, GR Cutter, Y Liu… - …, 2017 - Wiley Online Library
Objective To identify potential pharmacokinetic interactions between the pharmaceutical
formulation of cannabidiol (CBD; Epidiolex) and the commonly used antiepileptic drugs …
formulation of cannabidiol (CBD; Epidiolex) and the commonly used antiepileptic drugs …
A systematic review of cannabidiol dosing in clinical populations
SA Millar, NL Stone, ZD Bellman… - British journal of …, 2019 - Wiley Online Library
Aims Cannabidiol (CBD) is a cannabis‐derived medicinal product with potential application
in a wide‐variety of contexts; however, its effective dose in different disease states remains …
in a wide‐variety of contexts; however, its effective dose in different disease states remains …
[HTML][HTML] Cannabinoids in the treatment of epilepsy: hard evidence at last?
E Perucca - Journal of epilepsy research, 2017 - ncbi.nlm.nih.gov
The interest in cannabis-based products for the treatment of refractory epilepsy has
skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ …
skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ …
The essential medicinal chemistry of cannabidiol (CBD)
This Perspective of the published essential medicinal chemistry of cannabidiol (CBD)
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …
Cannabidiol as a therapeutic target: evidence of its neuroprotective and neuromodulatory function in Parkinson's disease
F Patricio, AA Morales-Andrade… - Frontiers in …, 2020 - frontiersin.org
The phytocannabinoids of Cannabis sativa L. have, since ancient times, been proposed as a
pharmacological alternative for treating various central nervous system (CNS) disorders …
pharmacological alternative for treating various central nervous system (CNS) disorders …
Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure …
OBJECTIVE To assess the effect of oral cannabidiol (CBD) administration in addition to
conventional antiepileptic treatment on seizure frequency in dogs with idiopathic epilepsy …
conventional antiepileptic treatment on seizure frequency in dogs with idiopathic epilepsy …