Beyond “use it or lose it”: The impact of engagement on cognitive aging

EAL Stine-Morrow, IE Manavbasi - Annual Review of …, 2022 - annualreviews.org
Biologically based senescence processes and cumulative opportunities for experience
collectively give rise to profound changes in cognition in later adulthood, the trajectories of …

Distinct cognitive trajectories in late life and associated predictors and outcomes: a systematic review

Z Wu, AZZ Phyo, T Al-Harbi… - Journal of Alzheimer's …, 2020 - content.iospress.com
Background: Cognitive aging is a dynamic process in late life with significant heterogeneity
across individuals. Objective: To review the evidence for latent classes of cognitive …

Twelve months of time-restricted feeding improves cognition and alters microbiome composition independent of macronutrient composition

AR Hernandez, C Watson, QP Federico, R Fletcher… - Nutrients, 2022 - mdpi.com
Declining health, gut dysbiosis, and cognitive impairments are hallmarks of advanced age.
While caloric restriction is known to robustly extend the healthspan and alter gut microbiome …

Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates

L Nyberg, M Andersson, A Lundquist… - Cerebral …, 2023 - academic.oup.com
It is well documented that some brain regions, such as association cortices, caudate, and
hippocampus, are particularly prone to age-related atrophy, but it has been hypothesized …

Leveraging technology to personalize cognitive enhancement methods in aging

DA Ziegler, JA Anguera, CL Gallen, WY Hsu, PE Wais… - Nature aging, 2022 - nature.com
As population aging advances at an increasing rate, efforts to help people maintain or
improve cognitive function late in life are critical. Although some studies have shown …

Hypertension and age-related cognitive impairment: common risk factors and a role for precision aging

M Hay, C Barnes, M Huentelman, R Brinton… - Current Hypertension …, 2020 - Springer
Abstract Purpose of Review Precision Aging® is a novel concept that we have recently
employed to describe how the model of precision medicine can be used to understand and …

Profiling the research landscape on cognitive aging: A bibliometric analysis and network visualization

Z Othman, AS Abdul Halim, KF Azman… - Frontiers in aging …, 2022 - frontiersin.org
Objectives This study aimed to profile the cognitive aging research landscape from 1956 to
2021. Methods A total of 3,779 documents were retrieved from the Scopus database for the …

Technological readiness and implementation of genomic‐driven precision medicine for complex diseases

PW Franks, E Melén, M Friedman… - Journal of Internal …, 2021 - Wiley Online Library
The fields of human genetics and genomics have generated considerable knowledge about
the mechanistic basis of many diseases. Genomic approaches to diagnosis, prognostication …

Cognitive aging and the life course: A new look at the scaffolding theory

PA Reuter-Lorenz, DC Park - Current Opinion in Psychology, 2023 - Elsevier
Our understanding of human neurocognitive aging, its developmental roots, and life course
influences has been transformed by brain imaging technologies, increasing availability of …

Cognitive trajectories in community-dwelling older adults and incident dementia, disability and death: A 10-year longitudinal study

Z Wu, RL Woods, TTJ Chong, SG Orchard… - Frontiers in …, 2022 - frontiersin.org
Objective The inter-individual variability in cognitive changes may be early indicators of
major health events. We aimed to determine whether late-life cognitive trajectories were …