Cancer stem cells (CSCs) in drug resistance and their therapeutic implications in cancer treatment

LTH Phi, IN Sari, YG Yang, SH Lee, N Jun… - Stem cells …, 2018 - Wiley Online Library
Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are suggested to be
responsible for drug resistance and cancer relapse due in part to their ability to self‐renew …

Non-coding RNAs and potential therapeutic targeting in cancer

S Toden, TJ Zumwalt, A Goel - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …

Emerging role of tumor cell plasticity in modifying therapeutic response

S Qin, J Jiang, Y Lu, EC Nice, C Huang… - Signal transduction and …, 2020 - nature.com
Resistance to cancer therapy is a major barrier to cancer management. Conventional views
have proposed that acquisition of resistance may result from genetic mutations. However …

Stem cell fate in cancer growth, progression and therapy resistance

NK Lytle, AG Barber, T Reya - Nature Reviews Cancer, 2018 - nature.com
Although we have come a long way in our understanding of the signals that drive cancer
growth, and how these signals can be targeted, effective control of this disease remains a …

MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

L Zhang, Y Liao, L Tang - Journal of Experimental & Clinical Cancer …, 2019 - Springer
Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human
cancers and regarded as a tumor suppressive microRNA because of its synergistic effect …

Recent insights into the nutritional immunomodulation of cancer‐related microRNAs

TÖ Şahin, B Yılmaz, N Yeşilyurt, D Cicia… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the most common cause of death worldwide, following cardiovascular diseases.
Cancer is a multifactorial disease and many reasons such as physical, chemical, biological …

Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells

U Testa, E Pelosi, G Castelli - Medical Sciences, 2018 - mdpi.com
Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …

[HTML][HTML] MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer

G Bertoli, C Cava, I Castiglioni - Theranostics, 2015 - ncbi.nlm.nih.gov
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …

Implications of the hybrid epithelial/mesenchymal phenotype in metastasis

MK Jolly, M Boareto, B Huang, D Jia, M Lu… - Frontiers in …, 2015 - frontiersin.org
Transitions between epithelial and mesenchymal phenotypes–the epithelial to
mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition …

circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a

R He, P Liu, X Xie, Y Zhou, Q Liao, W Xiong… - Journal of experimental …, 2017 - Springer
Backgroud Accumulating evidences indicate that circular RNAs (circRNAs), a class of non-
coding RNAs, play important roles in tumorigenesis. However, the function of circRNAs in …